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Condensed Statements of Cash Flows - USD ($)
6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Operating activities    
Net loss $ (9,039,632) $ (13,743,029)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 53,723 53,518
Stock-based compensation expense 2,062,924 1,710,423
Amortization of premium on marketable securities 9,595 27,475
Accrued interest included in convertible note payable 279,452 0
Changes in operating assets and liabilities:    
Other receivables (4,500,000) 0
Prepaid and other current assets (136,433) 1,105,208
Other assets (872,111) 0
Accounts payable and accrued expenses 3,262,191 (453,147)
Accrued compensation (985,135) (195,343)
Deferred revenue (10,006,507) 0
Deferred rent (13,847) (7,700)
Net cash used in operating activities (19,885,780) (11,502,595)
Investing activities    
Maturities of marketable securities 28,309,000 24,347,000
Purchase of marketable securities (81,836,441) (18,462,944)
Capital expenditures (20,682) (107,165)
Net cash (used in) provided by investing activities (53,548,123) 5,776,891
Financing activities    
Proceeds from issuance of convertible promissory note, net 12,500,000 0
Principal payment on promissory note (1,000,000) 0
Proceeds from issuance of common stock, net 30,740,665 5,275,872
Repurchase of common stock (11,202,542) 0
Proceeds from stock issuances under employee stock purchase plan and exercise of stock options 77,640 32,898
Net cash provided by financing activities 31,115,763 5,308,770
Net decrease in cash and cash equivalents (42,318,140) (416,934)
Cash and cash equivalents at beginning of period 58,083,409 13,876,090
Cash and cash equivalents at end of period 15,765,269 13,459,156
Supplemental disclosure of cash flow information:    
Cash paid for interest 4,861 35,000
Supplemental schedule of noncash financing activities:    
Costs related to issuance of common stock included in accounts payable and accrued expenses $ 131,122 $ 0