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Income Taxes - Effective Income Tax Rate Reconciliation (Details)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Income Tax Disclosure [Abstract]      
U.S. federal income tax at statutory rate 21.00% 21.00% 21.00%
State taxes (net of federal benefit) 2.84% 3.26% 5.02%
Stock-based compensation (1.48%) (5.18%) (3.24%)
Permanent differences (0.24%) (0.36%) (0.18%)
Federal research and development credit 1.92% 0.58% 1.77%
Change in valuation allowance (14.62%) (11.62%) (20.12%)
Other (0.35%) (0.82%) 0.26%
Acquisition costs 0.00% 0.00% (0.02%)
Expiration of tax attribute carryforwards (8.75%) (7.63%) (4.54%)
Effective income tax rate 0.32% (0.77%) (0.05%)