Income Taxes Income Taxes (Tables)

12 Months Ended

Dec. 31, 2022

Income Tax Disclosure [Abstract]

Schedule of Deferred Tax Assets and Liabilities

The following table represents the significant components of our deferred tax assets and liabilities for the periods presented:

	December 31,
	2022		2021
Deferred income tax assets
Net operating loss carryforwards	$	164,242	$	143,917
Business interest limitation carryforwards	34,445		35,234
Tax credit carryforwards	23,240		18,828
Lease liabilities	15,019		17,396
Capitalized research and development costs	32,216		—
Other	30,719		23,152
Gross deferred income tax assets	299,881		238,527
Valuation allowance	(245,212)		(176,872)
Total deferred income tax assets, net of valuation allowance	54,669		61,655
Deferred income tax liabilities
Intangible assets	(40,069)		(48,250)
Right-of-use assets	(11,225)		(13,465)
Other	(3,618)		(1,141)
Total deferred income tax liabilities	(54,912)		(62,856)
Net deferred income tax assets and liabilities	$	(243)	$	(1,201)

Summary of Operating Loss Carryforwards

The following table represents our net operating loss ("NOL") carryforwards as of December 31, 2022 and 2021:

	December 31,
	2022		2021
Federal	$	651,498	$	611,296
Various states	34,718		18,777
Foreign	5,255		3,213

Schedule of Effective Income Tax Rate Reconciliation

The following table is a reconciliation of the U.S. federal income tax at statutory rate to our effective income tax rate:

	December 31,
	2022		2021		2020
U.S. federal income tax at statutory rate	21.00	%	21.00	%	21.00	%
State taxes (net of federal benefit)	4.89		9.06		25.23
Stock-based compensation	(2.53)		14.88		69.14
Permanent differences	(0.14)		(0.12)		(1.03)
Federal research and development credit	1.38		5.41		20.42
Change in valuation allowance	(21.29)		(41.89)		(132.88)
Other	0.20		(1.62)		1.32
Acquisition costs	(0.01)		(1.44)		—
Extinguishment of convertible notes	—		—		(3.20)
Expiration of tax attribute carryforwards	(3.53)		—		—
Effective income tax rate	(0.03)	%	5.28	%	—	%

Schedule of Components of Income Tax Benefit

The following table summarizes the components of our income tax benefit for the periods presented:

	December 31,
	2022		2021		2020
Current income tax expense:
U.S. - State	$	1,084	$	1,215	$	—
Total current income tax expense	1,084		1,215		—
Deferred income tax benefit:
U.S. - Federal	97		—		—
U.S. - State	(1,055)		(7,322)		—
Total deferred income tax benefit	(958)		(7,322)		—
Total income tax benefit	$	126	$	(6,107)	$	—

Schedule of Unrecognized Tax Benefits Roll Forward

The following table summarizes the activity related to unrecognized tax benefits:

	December 31,
	2022		2021		2020
Unrecognized benefit—beginning of year	$	4,692	$	3,105	$	2,159
Gross (decreases) increases—prior year tax positions	(210)		32		—
Gross increases—current year tax positions	1,327		1,555		946
Unrecognized benefit—end of year	$	5,809	$	4,692	$	3,105