The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
APPLE INC COM 037833100 16,258 41,000 SH   SOLE 0 41,000 0 0
ALKERMES PLC SHS G01767105 48,756 1,700,000 SH   SOLE 0 1,700,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 4,484 144,647 SH   SOLE 0 144,647 0 0
ANADARKO PETROLEUM CORP COM 032511107 3,609 42,000 SH   SOLE 0 42,000 0 0
BANK OF AMERICA CORP COM 060505104 3,138 244,000 SH   SOLE 0 244,000 0 0
RESEARCH IN MOTION COM 760975102 23,117 2,210,000 SH   SOLE 0 2,210,000 0 0
BARNES & NOBLE INC COM 067774109 13,965 875,000 SH   SOLE 0 875,000 0 0
BMC SOFTWARE INC COM 055921100 6,634 147,000 SH   SOLE 0 147,000 0 0
CARNIVAL CORP CTF 143658300 1,564 45,600 SH   SOLE 0 45,600 0 0
DELTA AIR LINES INC COM 247361702 2,320 124,000 SH   SOLE 0 124,000 0 0
ENDOCYTE INC COM 29269A102 4,399 335,000 SH   SOLE 0 335,000 0 0
EXELIXIS INC COM 30161Q104 54,480 12,000,000 SH   SOLE 0 12,000,000 0 0
GOOGLE INC-CL A CL A 38259P508 76,856 87,300 SH   SOLE 0 87,300 0 0
HALLIBURTON CO COM 406216101 2,295 55,000 SH   SOLE 0 55,000 0 0
HEWLETT-PACKARD CO COM 428236103 41,575 1,676,423 SH   SOLE 0 1,676,423 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 4,048 250,000 SH   SOLE 0 250,000 0 0
ISIS PHARMACEUTICALS INC COM 464330109 13,972 520,000 SH   SOLE 0 520,000 0 0
INTERMUNE INC COM 45884X103 13,228 1,375,000 SH   SOLE 0 1,375,000 0 0
LIBERTY GLOBAL PLC-SERIES C CL C G5480U120 11,491 169,254 SH   SOLE 0 169,254 0 0
LIFE TECHNOLOGIES CORP COM 53217V109 16,058 217,000 SH   SOLE 0 217,000 0 0
MERCK & CO.INC. COM 58933Y105 86,704 1,866,600 SH   SOLE 0 1,866,600 0 0
MICROSOFT CORP COM 594918104 691 20,000 SH   SOLE 0 20,000 0 0
MICRON TECHNOLOGY INC COM 595112103 3,325 232,000 SH   SOLE 0 232,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 3,613 270,000 SH   SOLE 0 270,000 0 0
NASDAQ OMX GROUP/THE COM 631103108 4,092 124,793 SH   SOLE 0 124,793 0 0
NEKTAR THERAPEUTICS COM 640268108 16,748 1,450,000 SH   SOLE 0 1,450,000 0 0
NYSE EURONEXT COM 629491101 32,129 776,070 SH   SOLE 0 776,070 0 0
ONYX PHARMACEUTICALS INC COM 683399109 83,530 962,103 SH   SOLE 0 962,103 0 0
OPTIMER PHARMACEUTICALS INC COM 68401H104 6,873 475,000 SH   SOLE 0 475,000 0 0
OREXIGEN THERAPEUTICS INC COM 686164104 11,106 1,900,000 SH   SOLE 0 1,900,000 0 0
PACIFIC DRILLING SA SHS L7257P106 2,690 275,000 SH   SOLE 0 275,000 0 0
RIGEL PHARMACEUTICALS INC COM 766559603 3,006 900,000 SH   SOLE 0 900,000 0 0
SMITHFIELD FOODS INC COM 832248108 21,320 651,000 SH   SOLE 0 651,000 0 0
SHIRE PLC-ADR ADR 82481R106 6,658 70,000 SH   SOLE 0 70,000 0 0
SEQUENOM INC COM 817337405 2,947 700,000 SH   SOLE 0 700,000 0 0
UNIVERSAL HEALTH SERVICES-B CL B 913903100 6,696 100,000 SH   SOLE 0 100,000 0 0
URS CORP COM 903236107 16,999 360,000 SH   SOLE 0 360,000 0 0
VALE SA-SP ADR ADR 91912E105 2,885 219,400 SH   SOLE 0 219,400 0 0
VIVUS INC COM 928551100 52,928 4,207,296 SH   SOLE 0 4,207,296 0 0
WARNER CHILCOTT PLC-CL A SHS G94368100 11,268 566,000 SH   SOLE 0 566,000 0 0