X0303 4 2010-12-01 0 0001339455 Somaxon Pharmaceuticals, Inc. SOMX 0001380762 Dorsey Brian C/O SOMAXON PHARMACEUTICALS, INC. 3570 CARMEL MOUNTAIN ROAD, SUITE 100 SAN DIEGO CA 92130 0 1 0 0 SVP, Technical Operations Common Stock 2010-12-01 4 S 0 8468 2.6839 D 43452 D This sale of shares of common stock underlying vested restricted stock units was effected by the reporting person pursuant to a Rule 10b5-1 trading plan adopted by the reporting person, with the proceeds remitted to the Company to cover the taxes withheld upon the vesting of 22,500 restricted stock units on December 1, 2010. Reflects the weighted average sale price of the shares sold. The shares were sold in multiple trades at prices ranging from $2.62 to $2.79 per share. The reporting person will provide to the SEC staff, the issuer or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price. /s/ Matthew W. Onaitis, Attorney-in-fact 2010-12-03