Property and equipment, net

6 Months Ended

Jun. 30, 2022

Property and equipment, net

Property and equipment, net

7. Property and equipment, net

Property and equipment, net consisted of the following (in thousands):

	June 30,		December 31,
	2022		2021
Manufacturing and laboratory equipment	$	11,737	$	13,277
Computer hardware and software		1,553		1,742
Office furniture and fixtures		580		745
Leasehold improvements		8,243		3,012
Construction-in-process		1,001		4,313
		23,114		23,089
Less: Accumulated depreciation		(10,465)		(11,785)
	$	12,649	$	11,304

Depreciation and amortization expense related to property and equipment was $0.6 million and $0.3 million for the three months ended June 30, 2022 and 2021, respectively. Depreciation and amortization expense related to property and equipment was $1.1 million and $0.7 million for the six months ended June 30, 2022 and 2021, respectively. The Company had $2.3 million and less than $0.1 million fully depreciated assets disposed of during the three months ended June 30, 2022 and 2021, respectively, and $2.3 million and less than $0.1 million fully depreciated assets disposed of during the six months ended June 30, 2022 and 2021, respectively.