X0306 4 2021-07-19 0 0001380106 RAPID MICRO BIOSYSTEMS, INC. RPID 0001647491 Longitude Capital Partners II, LLC 2740 SAND HILL ROAD, SECOND FLOOR MENLO PARK CA 94025 0 0 1 0 0001527510 Longitude Venture Partners II, L.P. 2740 SAND HILL ROAD, SECOND FLOOR MENLO PARK CA 94025 0 0 1 0 0001865779 Longitude Prime Partners, LLC 2740 SAND HILL ROAD, SECOND FLOOR MENLO PARK CA 94025 0 0 1 0 0001865844 Longitude Prime Fund, L.P. 2740 SAND HILL ROAD, SECOND FLOOR MENLO PARK CA 94025 0 0 1 0 0001253886 ENRIGHT PATRICK G 2740 SAND HILL ROAD, SECOND FLOOR MENLO PARK CA 94025 0 0 1 0 0001431159 Tammenoms Bakker Juliet 2740 SAND HILL ROAD, SECOND FLOOR MENLO PARK CA 94025 0 0 1 0 Class A Common Stock 2021-07-19 4 C 0 3344038 0.00 A 3407952 I Held by Longitude Venture Partners II, L.P. Class A Common Stock 2021-07-19 4 P 0 150000 20.00 A 150000 I Held by Longitude Prime Fund, L.P. Series A1 Preferred Stock 2021-07-19 4 C 0 8774007 0.00 D Class A Common Stock 1754801 0 I Held by Longitude Venture Partners II, L.P. Series B1 Preferred Stock 2021-07-19 4 C 0 5654529 0.00 D Class A Common Stock 1130904 0 I Held by Longitude Venture Partners II, L.P. Series C1 Preferred Stock 2021-07-19 4 C 0 2291665 0.00 D Class A Common Stock 458333 0 I Held by Longitude Venture Partners II, L.P. Series A1 Warrant 0.01 2021-07-19 4 C 0 2500000 0.00 D 2027-07-24 Series A1 Preferred Stock 2500000 0 I Held by Longitude Venture Partners II, L.P. Common Stock Warrant 0.05 2021-07-19 4 C 0 500000 0.00 A 2027-07-24 Class A Common Stock 500000 500000 I Held by Longitude Venture Partners II, L.P. Series B1 Warrant 0.01 2021-07-19 4 C 0 645160 0.00 D 2028-01-17 Series B1 Preferred Stock 645160 0 I Held by Longitude Venture Partners II, L.P. Common Stock Warrant 0.05 2021-07-19 4 C 0 129032 0.00 A 2028-01-17 Class A Common Stock 129032 129032 I Held by Longitude Venture Partners II, L.P. The securities are held directly by Longitude Venture Partners II, L.P. ("LVP II"). Longitude Capital Partners II, LLC, ("LCP II"), the general partner of LVP II, may be deemed to have voting and investment power with respect to the shares held by LVP II. Patrick G. Enright and Juliet Tammenoms Bakker are the managing members of LCP II and may be deemed to share voting and investment power over the shares held by LVP II. Each of LCP II, Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interest therein. The securities are held directly by Longitude Prime Fund, L.P. ("LPF"). Longitude Prime Partners, LLC ("LPP"), the general partner of LPF, may be deemed to have voting and investment power with respect to the shares held by LPF. Mr. Enright and Ms. Tammenoms Bakker are the managing members of LPP and may be deemed to have voting, investment and dispositive power over the shares held by LPF. LPP and each of Mr. Enright and Ms. Tammenoms Bakker disclaim beneficial ownership of such shares except to the extent of their respective pecuniary interests therein. The Series A1 Preferred Stock, Series B1 Preferred Stock and Series C1 Preferred Stock (collectively, the "Preferred Stock") are convertible at any time, at the holder's election and have no expiration date. Each share of Preferred Stock automatically converted into 0.20 shares of the Issuer's Class A Common Stock upon the closing of the Issuer's initial public offering. The Issuer's Preferred Stock warrants automatically converted into warrants to purchase Common Stock immediately prior to the closing of the Issuer's initial public offering without payment or further consideration. The transaction is listed solely for the purpose of reporting the change in the shares underlying the warrants. Immediately exercisable. Longitude Capital Partners II, LLC, By: /s/ Patrick Enright, managing member 2021-07-20 Longitude Venture Partners II, L.P., By: /s/ Patrick Enright, managing member of the general partner 2021-07-20 Longitude Prime Partners, LLC, By: /s/ Patrick Enright, managing member 2021-07-20 Longitude Prime Fund, L.P., By: /s/ Patrick Enright, managing member of the general partner 2021-07-20 /s/ Patrick Enright 2021-07-20 /s/ Juliet Tammenoms Bakker 2021-07-20