ACADIA PHARMACEUTICALS INC COM 004225108 2411 90188 SH SOLE 0 0 90188 ALEXION PHARMACEUTICALS INC COM 015351109 2388 18235 SH SOLE 0 0 18235 ALLIANCE DATA SYSTEMS CORP COM 018581108 1826 13028 SH SOLE 0 0 13028 AMARIN CORP PLC SPONS ADR NEW 023111206 2564 132255 SH SOLE 0 0 132255 AMICUS THERAPEUTICS INC COM 03152W109 2403 192533 SH SOLE 0 0 192533 ARCOSA INC COM 039653100 1967 52264 SH SOLE 0 0 52264 ARRAY BIOPHARMA INC COM 04269X105 4011 86567 SH SOLE 0 0 86567 ASCENDIS PHARMA A S SPONSORED ADR 04351P101 2111 18334 SH SOLE 0 0 18334 BAUSCH HEALTH COS INC COM 071734107 1970 78121 SH SOLE 0 0 78121 BEIGENE LTD SPONSORED ADR 07725L102 2207 17807 SH SOLE 0 0 17807 BERKSHIRE HATHAWAY INC DEL CL A 084670108 37247 117 SH SOLE 0 0 117 BIOCRYST PHARMACEUTICALS COM 09058V103 2447 645583 SH SOLE 0 0 645583 BIOMARIN PHARMACEUTICAL INC COM 09061G101 2251 26278 SH SOLE 0 0 26278 BLUEPRINT MEDICINES CORP COM 09627Y109 2599 27551 SH SOLE 0 0 27551 CBRE GROUP INC CL A 12504L109 2003 39052 SH SOLE 0 0 39052 CITIGROUP INC COM NEW 172967424 2027 28938 SH SOLE 0 0 28938 COCRYSTAL PHARMA INC COM PAR 19188J300 359 152916 SH SOLE 0 0 152916 EIDOS THERAPEUTICS INC COM 28249H104 2606 83836 SH SOLE 0 0 83836 GENOMIC HEALTH INC COM 37244C101 2499 42966 SH SOLE 0 0 42966 GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 2070 39349 SH SOLE 0 0 39349 HERON THERAPEUTICS INC COM 427746102 2398 129020 SH SOLE 0 0 129020 HOME DEPOT INC COM 437076102 378 1819 SH SOLE 0 0 1819 INCYTE CORP COM 45337C102 2440 28714 SH SOLE 0 0 28714 INFLARX NV COM N44821101 185 58449 SH SOLE 0 0 58449 IOVANCE BIOTHERAPEUTICS INC COM 462260100 3213 131041 SH SOLE 0 0 131041 JD COM INC SPON ADR CL A 47215P106 12041 397528 SH SOLE 0 0 397528 KKR & CO INC CL A 48251W104 1944 76943 SH SOLE 0 0 76943 MADRIGAL PHARMACEUTICALS INC COM 558868105 2424 23131 SH SOLE 0 0 23131 MEIRAGTX HOLDINGS PLC COM G59665102 2566 95462 SH SOLE 0 0 95462 MIRATI THERAPEUTICS INC COM 60468T105 3160 30680 SH SOLE 0 0 30680 MORGAN STANLEY COM NEW 617446448 1897 43300 SH SOLE 0 0 43300 MYOVANT SCIENCES LTD COM G637AM102 1611 177988 SH SOLE 0 0 177988 NEUROCRINE BIOSCIENCES INC COM 64125C109 2450 29020 SH SOLE 0 0 29020 ORCHARD THERAPEUTICS PLC ADS 68570P101 1726 123400 SH SOLE 0 0 123400 RA PHARMACEUTICALS INC COM 74933V108 2944 97916 SH SOLE 0 0 97916 RETROPHIN INC COM 761299106 2483 123600 SH SOLE 0 0 123600 RHYTHM PHARMACEUTICALS INC COM 76243J105 1897 86208 SH SOLE 0 0 86208 SEAGATE TECHNOLOGY PLC SHS G7945M107 1992 42275 SH SOLE 0 0 42275 SEATTLE GENETICS INC COM 812578102 2325 33593 SH SOLE 0 0 33593 SLM CORP COM 78442P106 1855 190827 SH SOLE 0 0 190827 SPDR S&P 500 ETF TR TR UNIT 78462F103 276 942 SH SOLE 0 0 942 SUMMIT MIDSTREAM PARTNERS LP COM UNIT LTD 866142102 651 87560 SH SOLE 0 0 87560 SYNTHORX INC COM 87167A103 2041 151048 SH SOLE 0 0 151048 TRINITY INDS INC COM 896522109 1880 90599 SH SOLE 0 0 90599 WAVE LIFE SCIENCES LTD SHS Y95308105 2465 94475 SH SOLE 0 0 94475 ZOGENIX INC COM NEW 98978L204 2862 59905 SH SOLE 0 0 59905