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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Cash Flows from Operating Activities    
Net (loss) income $ (11,655) $ 207,340
Adjustments to reconcile net (loss) income to net cash provided by (used in) operating activities:    
Stock-based compensation 13,802 9,352
Non-cash lease expense 569 584
Depreciation 239 236
Accretion of discount on marketable securities (2,289) (1,615)
Net realized loss on sale of marketable securities 5 0
Changes in operating assets and liabilities:    
Receivable from collaboration partner 165,000 (290,043)
Contract asset (22,825)  
Prepaid expenses and other assets (948) (915)
Accounts payable 1,237 2,825
Accrued expenses and other payables (11,817) (2,870)
Deferred revenue (5,496) 45,047
Income taxes payable (800) 3,326
Operating lease liability 341  
Operating lease liability   (696)
Net cash provided by (used in) operating activities 125,363 (27,429)
Cash Flows from Investing Activities    
Purchase of marketable securities (214,040) (65,671)
Proceeds from maturities of marketable securities 113,180 71,984
Proceeds from sale of marketable securities 7,003  
Purchases of property and equipment (545) (242)
Net cash (used in) provided by investing activities (94,402) 6,071
Cash Flows from Financing Activities    
Proceeds from issuance of common stock upon exercise of stock options and purchases under employee stock purchase plan 11,922 7,799
Tax withholding payments related to net settlement of restricted stock units (479) (600)
Net cash provided by financing activities 11,443 7,199
Net increase (decrease) in cash, cash equivalents and restricted cash 42,404 (14,159)
Cash, cash equivalents and restricted cash, beginning of period 97,474 186,952
Cash, cash equivalents and restricted cash, end of period 139,878 172,793
Supplemental Disclosure of Non-Cash Financing and Investing Information:    
Purchases of property and equipment in accounts payable and accrued liabilities $ 33 $ 45