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Stockholders' Equity (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Aug. 05, 2022
Jul. 01, 2022
Nov. 27, 2019
Aug. 31, 2022
Jan. 31, 2022
Jun. 30, 2021
Oct. 31, 2019
Dec. 31, 2018
Aug. 31, 2018
Sep. 30, 2022
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2019
Dec. 31, 2021
Aug. 06, 2018
Stock transactions                              
Warrants issued to purchase common stock, number of shares   400,000                          
Common stock sold                   49,198,411 49,198,411     47,838,330  
Warrants to purchase, aggregate number of shares outstanding                   0 0        
Number of warrants exercised                         600,000    
Issuance of common stock upon exercise of Exchange Warrants (in shares)   399,997                     599,997    
Proceeds from public offering of common stock, net of issuance costs                     $ 14,553 $ 123,995      
Par value (per share)                   $ 0.00001 $ 0.00001     $ 0.00001  
2019 Form S-3                              
Stock transactions                              
Common stock available for sale                   $ 79,300 $ 79,300        
Maximum aggregate offering price             $ 250,000                
2019 Sales Agreement                              
Stock transactions                              
Common stock issued (in shares)         422,367                    
Common stock available for sale                   $ 17,000 $ 17,000        
Maximum aggregate offering price     $ 250,000       $ 75,000                
Proceeds from public offering of common stock, net of issuance costs         $ 14,600                    
2022 Form S-3                              
Stock transactions                              
Maximum aggregate offering price       $ 300,000                      
2022 Sales Agreement                              
Stock transactions                              
Maximum aggregate offering price $ 300,000     $ 100,000                      
Underwritten public offering                              
Stock transactions                              
Net proceeds from sale of common stock           $ 123,800                  
Common stock issued (in shares)           3,046,358                  
Common stock issued, price per share           $ 37.75                  
underwritten public offering, Additional offering                              
Stock transactions                              
Common stock issued (in shares)           456,953                  
Common stock issued, price per share           $ 37.75                  
Common Stock                              
Stock transactions                              
Common stock issued (in shares)                       3,503,311      
Issuance of common stock upon exercise of Exchange Warrants (in shares)                   399,997 399,997        
Common Stock | Private Placement                              
Stock transactions                              
Number of warrants exercised                   0 0        
Investors | Private Placement                              
Stock transactions                              
Aggregate shares of common stock sold                 2,750,000            
Common stock sold, price per share                 $ 8.00            
Net proceeds from sale of common stock                 $ 21,700            
Warrants issued to purchase common stock, number of shares                             2,750,000
Warrants exercisable date                 Aug. 08, 2023            
Exchange Agreement | Exchanging Stockholders                              
Stock transactions                              
Equity method investment, ownership percentage               9.99%              
Exchange Agreement | Exchanging Stockholders                              
Stock transactions                              
Warrants issued to purchase common stock, number of shares               1,000,000              
Exercise Price (per share)               $ 0.00001              
Common stock exchanged for pre-funded warrants               1,000,000              
Par value (per share)               $ 0.00001              
Duration of warrants from date of issuance (in years)               10 years              
$10.00 per share | Investors | Private Placement                              
Stock transactions                              
Warrants to purchase common stock (in shares)                             1,375,000
Exercise Price (per share)                             $ 10.00
$15.00 per share | Investors | Private Placement                              
Stock transactions                              
Warrants to purchase common stock (in shares)                             1,375,000
Exercise Price (per share)                             $ 15.00