Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 152,816	$ 123,665
Marketable securities	114,621	203,235
Receivable from collaboration partner and contract asset - related party	125	1,566
Research and development tax incentive receivable		2,792
Prepaid expenses and other current assets	9,055	9,478
Total current assets	276,617	340,736
Property and equipment, net	1,783	1,798
Restricted cash - noncurrent	225	225
Operating lease right-of-use asset	3,549	4,936
Total assets	282,174	347,695
Current liabilities:
Accounts payable	4,715	1,600
Payable to collaboration partner - related party	32	899
Accrued expenses and other payables	29,574	37,716
Deferred revenue - related party		1,601
Operating lease liability - current	2,433	2,200
Total current liabilities	36,754	44,016
Operating lease liability - noncurrent	1,804	3,658
Total liabilities	38,558	47,674
Commitments and contingencies
Stockholders' equity:
Preferred stock, $0.00001 par value, 10,000,000 shares authorized; no shares issued and outstanding
Common stock, $0.00001 par value, 90,000,000 shares authorized; 49,198,411 and 47,838,330 shares issued and outstanding as of September 30, 2022 and December 31, 2021, respectively
Additional paid-in capital	746,657	709,682
Accumulated other comprehensive loss	(480)	(299)
Accumulated deficit	(502,561)	(409,362)
Total stockholders' equity	243,616	300,021
Total liabilities and stockholders' equity	$ 282,174	$ 347,695