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Organization and Description of Business - Liquidity (Details)
$ in Thousands
12 Months Ended
Dec. 31, 2021
USD ($)
segment
Dec. 31, 2020
USD ($)
Organization and Description of Business    
Number of operating segments | segment 1  
Net losses from operations since inception    
Cash, cash equivalents and marketable securities $ 326,900  
Accumulated deficit $ (409,362) $ (283,811)