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Consolidated Statements of Operations - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Consolidated Statements of Operations      
License and collaboration revenue - related party $ 231 $ 30,925 $ 20,063
Operating expenses:      
Research and development 65,003 59,497 46,181
General and administrative 15,749 13,697 11,779
Total operating expenses 80,752 73,194 57,960
Loss from operations (80,521) (42,269) (37,897)
Interest income 2,813 2,566 948
Interest expense (169)    
Other expense, net (1) (20) (8)
Loss before income tax benefit (77,878) (39,723) (36,957)
Income tax benefit 691 799  
Net loss $ (77,187) $ (38,924) $ (36,957)
Net loss per share, basic and diluted $ (2.98) $ (1.74) $ (2.09)
Weighted-average shares used to compute net loss per share, basic and diluted 25,894,024 22,364,515 17,694,505