Income Taxes (Tables)

12 Months Ended

Dec. 31, 2019

Income Taxes

Schedule of domestic and foreign components of net loss

The following table presents domestic and foreign components of net loss before income taxes (in thousands):

	Year Ended December 31,
	2019		2018		2017
Domestic	$	(72,271)	$	(37,511)	$	(34,556)
Foreign		(5,607)		(2,212)		(2,401)
Total net loss before taxes	$	(77,878)	$	(39,723)	$	(36,957)

Schedule of federal, state and foreign of the income tax expense (benefit)

		Year Ended December 31,
	2019		2018		2017
Current:
Federal	$	—	$	—	$	—
State		—		—		—
Foreign		84		—		—
Total current tax expense		84		—		—
Deferred:
Federal		—		—		—
State		—		—		—
Foreign		(775)		(799)		—
Total deferred tax benefit		(775)		(799)		—
Income tax benefit	$	(691)	$	(799)	$	—

Schedule of provision differences from federal statutory rate

	Year Ended December 31,
	2019		2018		2017
Federal statutory income tax rate	21.0	%	21.0	%	34.0	%
State taxes, net of federal benefit	1.2		7.0		0.5
Research and development credits	4.3		(1.3)		2.6
Foreign tax rate difference	0.7		0.4		(1.2)
Change in valuation allowance	(23.8)		(22.2)		(5.2)
Change in tax law	—		—		(31.2)
Other	(2.5)		(2.9)		0.5
Provision for income taxes	0.9	%	2.0	%	—	%

Schedule of components of deferred tax assets

The components of the deferred tax assets are as follows (in thousands):

	December 31,
	2019		2018
Deferred tax assets:
Net operating loss carryforwards	$	39,907	$	27,704
Depreciation and amortization		318		269
Accruals/other		5,454		2,455
Operating lease liability		1,516		—
Research and development credits		8,038		4,270
Total deferred tax assets		55,233		34,698
Deferred tax liabilities:
Operating right-of-use asset		(1,269)		—
Total deferred tax liabilities		(1,269)		—
Valuation allowance		(52,531)		(34,040)
Net deferred tax assets	$	1,433	$	658

Schedule of reconciliation of beginning and ending unrecognized tax benefits

A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows (in thousands):

	Year Ended December 31,
	2019		2018		2017
Balance at beginning of year	$	9,466	$	5,414	$	2,131
Increase based on tax positions related to prior years		184		108		—
Increase based on tax positions related to current year		6,981		3,944		3,283
Balance at end of year	$	16,631	$	9,466	$	5,414