144 0001376960 XXXXXXXX LIVE 0000886163 LIGAND PHARMACEUTICALS INC 001-33093 3911 SORRENTO VALLEY BLVD SUITE 110 SAN DIEGO CA 92121 858-550-7500 Aryeh Jason Director common Wells Fargo Clearing Services

1 North Jefferson Avenue St. Louis MO 63103

4500 1124879.82 20041061 06/11/2026 NASDAQ common 04/28/2005 Open Market Purchase Open Market N 4500 04/28/2005 cash N JALAA Equities LP

3911 Sorrento Valley Blvd. Suite 110 San Diego CA 92121

Ligand Pharmaceuticals, Inc. 06/10/2026 500 124980.42 shares were sold in account for JALAA Equities LP, Jason Aryeh as General Partner. 4,500 shares sold were acquired on 4/28/2005 and 4/29/2005. 06/11/2026 Jason Aryeh