X0306 4 2017-05-19 0 0001660719 Aralez Pharmaceuticals Inc. ARLZ 0001376960 Aryeh Jason C/O ARALEZ PHARMACEUTICALS INC., 7100 WEST CREDIT AVENUE, SUITE 101 MISSISSAUGA A6 L5N 0E4 ONTARIO, CANADA 1 0 0 0 Common Shares, without par value 2017-05-19 4 S 0 51041 1.5587 D 337644 I By JALAA Equities, LP Common Shares, without par value 2017-05-22 4 S 0 233468 1.4236 D 104176 I By JALAA Equities, LP Common Shares, without par value 2017-05-23 4 S 0 104176 1.4099 D 0 I By JALAA Equities, LP Common Shares, without par value 15000 D This transaction was executed in multiple trades at prices ranging from $1.50 to $1.60. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Includes 45,469 shares issued in connection with a previously exercised warrant. Securities are owned by JALAA Equities, LP, of which the Reporting Person is the general partner. By reason of the provisions of Rule 16a-1 under the Securities Exchange Act of 1934, as amended, the Reporting Person may be deemed to be the beneficial owner of the securities owned by JALAA Equities, LP. This transaction was executed in multiple trades at prices ranging from $1.40 to $1.51. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $1.40 to $1.42. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ Jason Aryeh 2017-05-24