X0306 4 2020-08-17 0 0001737953 Replimune Group, Inc. REPL 0001376493 Love Colin C/O REPLIMUNE GROUP, INC. 500 UNICORN PARK WOBURN MA 01801 0 1 0 0 Chief Operating Officer Common Stock 2020-08-17 4 S 0 9036 23.60 D 1042488 D Common Stock 2020-08-17 4 S 0 5964 23.19 D 1036524 D The sales reported on this Form 4 were made by the reporting person pursuant to a trading plan adopted on June 12, 2020 that is intended to comply with Rule 10b5-1(c) under the Securities Exchange Act of 1934, as amended. The price reported reflects a weighted average price. These shares were sold in multiple transactions at prices ranging from $23.29 to $24.28. The price reported reflects a weighted average price. These shares were sold in multiple transactions at prices ranging from $23.07 to $23.27. Following the sales reported on this Form 4, the reporting person continues to beneficially own 1,036,524 shares of the Issuer's common stock. The reporting person also holds options to acquire 444,653 shares of the Issuer's common stock, 188,185 of which are exercisable as of the date hereof. /s/ Jean Franchi, attorney-in-fact 2020-08-18