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Equity (Details) (USD $)
3 Months Ended 3 Months Ended
Mar. 31, 2013
Plan
Mar. 31, 2012
Mar. 31, 2013
Warrants [Member]
Dec. 31, 2012
Warrants [Member]
Mar. 31, 2013
Contingent Warrants Related to Private Placement of Common Stock [Member]
Warrants [Member]
Mar. 31, 2013
Callable Warrants [Member]
Warrants [Member]
Mar. 31, 2013
Other [Member]
Warrants [Member]
Mar. 31, 2013
Cost of Products Sold [Member]
Mar. 31, 2012
Cost of Products Sold [Member]
Mar. 31, 2013
Research and Development [Member]
Mar. 31, 2012
Research and Development [Member]
Mar. 31, 2013
Selling, General and Administrative [Member]
Mar. 31, 2012
Selling, General and Administrative [Member]
Mar. 31, 2013
$0.50-$0.76 [Member]
Mar. 31, 2013
$0.87-$1.35 [Member]
Mar. 31, 2013
$1.40-$2.29 [Member]
Mar. 31, 2013
$2.33-$3.75 [Member]
Mar. 31, 2013
$3.85-$5.80 [Member]
Mar. 31, 2013
Stock Options [Member]
Mar. 31, 2013
Restricted Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Number of share-based compensation plans 3                                      
Outstanding assumed options (in shares) 375,000                                      
Additional shares authorized by Board of Directors (in shares) 6,000,000                                      
Shares authorized (in shares) 22,500,000                                      
Number of shares [Roll forward]                                        
Outstanding, beginning of period (in shares) 13,614,135                                      
Granted (in shares) 2,645,000                                      
Exercised (in shares) (170,099)                                      
Unvested options forfeited (in shares) (59,667)                                      
Vested options expired (in shares) (6,666)                                      
Outstanding, end of period (in shares) 16,022,703                                      
Vested at end of period (in shares) 6,853,995                                      
Exercisable options, vested and expected to vest (in shares) 15,641,584                                      
Weighted-Average Exercise Price [Roll forward]                                        
Outstanding, weighted average exercise price, beginning of period (in dollars per share) $ 1.42                                      
Granted, weighted average exercise price (in dollars per share) $ 5.04                                      
Exercised, weighted average exercise price (in dollars per share) $ 1.37                                      
Unvested options forfeited weighted-average exercise price (in dollars per share) $ 2.32                                      
Vested options expired weighted-average exercise price (in dollars per share) $ 1.15                                      
Outstanding, weighted average exercise price, end of period (in dollars per share) $ 2.02                                      
Vested at end of period weighted average exercise price (in dollars per share) $ 1.11                                      
Vested and expected to vest, weighted average exercise price (in dollars per share) $ 1.98                                      
Stock options, additional disclosures [Abstract]                                        
Vested at end of period weighted average remaining contractual term 6 years 8 months 12 days                                      
Vested and expected to vest, weighted average remaining contractual term 8 years 1 month 6 days                                      
Vested at end of period aggregate intrinsic value $ 27,258,080                                      
Vested and expected to vest, aggregate intrinsic value 48,645,480                                      
Exercised options, intrinsic value 613,000                                      
Expenses expected to be recognized over a weighted-average period                                     2 years 7 months 6 days 2 years 11 months 5 days
Number of shares granted (in shares)                                       250,000
Weighted-average grant date fair value (in dollars per share)                                       $ 5.07
Vesting period                                       3 years
Total unrecognized stock-based compensation related to time-based, nonvested restricted stock                                       1,262,000
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]                                        
Exercise Price Range, lower range limit (in dollars per share)                           $ 0.50 $ 0.87 $ 1.40 $ 2.33 $ 3.85    
Exercise Price Range, upper range limit (in dollars per share)                           $ 0.76 $ 1.35 $ 2.29 $ 3.75 $ 5.80    
Number of outstanding options (in shares) 16,022,703                         2,319,500 7,002,003 1,851,700 2,179,500 2,670,000    
Outstanding Options, weighted average remaining contractual term 8 years 1 month 6 days                         5 years 2 months 12 days 8 years 3 months 18 days 6 years 8 months 12 days 9 years 6 months 9 years 10 months 24 days    
Outstanding Options, weighted average exercise price (in dollars per share) $ 2.02                         $ 0.67 $ 1.19 $ 1.63 $ 2.75 $ 5.03    
Number of exercisable options (in shares) 6,853,995                         2,319,500 3,092,797 1,441,698 0 0    
Exercisable Options, weighted average exercise price (in dollars per share) $ 1.11                         $ 0.67 $ 1.19 $ 1.66 $ 0 $ 0    
Total unrecognized compensation expense 12,961,000                                      
Fair value options valuation assumptions [Abstract]                                        
Expected volatility (in hundredths) 64.30% 58.30%                                    
Expected life 6 years 6 years                                    
Expected dividend yield (in hundredths) 0.00% 0.00%                                    
Risk-free interest rate, minimum (in hundredths) 0.98%                                      
Risk-free interest rate, maximum (in hundredths) 1.86% 0.88%                                    
Weighted-average grant date fair value for options granted during the period (in dollars per share) $ 2.94                                      
Share-based Compensation [Abstract]                                        
Share-based compensation expense $ 984,792 $ 500,985           $ 50,162 $ 24,010 $ 75,978 $ 71,520 $ 858,652 $ 405,455              
Class of Warrant or Right [Line Items]                                        
Warrants, term 5 years                                      
Warrants, Number of Warrants [Roll Forward]                                        
Warrants outstanding, beginning of period (in shares)     2,344,002 3,129,168                                
Warrants exercised (in shares)         62,500 266,666 456,000                          
Warrants outstanding, end of period (in shares)     2,344,002 3,129,168                                
Warrants, Weighted-Average Exercise Price per Warrant [Roll Forward]                                        
Warrants outstanding, beginning of period (in dollars per share)     1.00 1.04                                
Warrants exercised (in dollars per share)         $ 0.01 $ 1.50 $ 1.15                          
Warrants outstanding, end of period (in dollars per share)     1.00 1.04