<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001375889</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001321732</issuerCik>
      <issuerName>Penumbra Inc</issuerName>
      <secFileNumber>001-37557</secFileNumber>
      <issuerAddress>
        <com:street1>ONE PENUMBRA PLACE</com:street1>
        <com:city>ALAMEDA</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>94502</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>(510) 995-2486</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Grewal Harpreet</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Director</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Fidelity Brokerage Services LLC</name>
        <address>
          <com:street1>245 Summer Street</com:street1>
          <com:city>Boston</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02110</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>170</noOfUnitsSold>
      <aggregateMarketValue>40968.30</aggregateMarketValue>
      <noOfUnitsOutstanding>38436663</noOfUnitsOutstanding>
      <approxSaleDate>10/02/2023</approxSaleDate>
      <securitiesExchangeName>NYSE</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <acquiredDate>09/30/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Stock Award vesting</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Penumbra, Inc.</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>170</amountOfSecuritiesAcquired>
      <paymentDate>09/30/2023</paymentDate>
      <natureOfPayment>N/A</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Harpreet Grewal</name>
        <address>
          <com:street1>c/o Penumbra, Inc</com:street1>
          <com:street2>One Penumbra Place</com:street2>
          <com:city>Alameda</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94502</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <saleDate>09/01/2023</saleDate>
      <amountOfSecuritiesSold>340</amountOfSecuritiesSold>
      <grossProceeds>90650.80</grossProceeds>
    </securitiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>10/02/2023</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>05/23/2023</planAdoptionDate>
      </planAdoptionDates>
      <signature>/s/ Myra King, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Harpreet Grewal</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
