Deferred Tax Assets Capitalized Start Up Costs
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from capitalized start-up costs.
Capitalized start-up costs
Capitalized Research and Development Expense
Represents the amount of research and development expenses, which were capitalized for tax purposes as start-up costs.
Capitalized start-up costs
Capitalized Research and Development Costs Amortization Period
The amortization period of capitalized research and development costs.
Amortization period of capitalized research and development costs
Operating Losses and Tax Credit Carryforwards [Table]
Tabular disclosure of information pertaining to net operating losses and tax credit carryforwards.
Operating Losses and Tax Credit Carryforwards [Line Items]
Net operating losses and tax credit carryforwards
Government Grants [Policy Text Block]
Government Grants
Disclosure of accounting policy for government grants.
Award Type [Axis]
Government Grants [Abstract]
Government Grants
Term A Loans
Represents the Term A Loans under the May 2010 Loan Facility availed by the entity.
Term A Loans [Member]
Term B Loans
Represents the Term B Loans under the May 2010 Loan Facility availed by the entity.
Term B Loans [Member]
Amendment Description
Document and Entity Information
Amendment Flag
Other Assets Equipment Funding
Other assets-equipment funding (note 9(c ))
Carrying value as of the balance sheet date of other assets-equipment funding that are expected to be realized or consumed after one year (or the normal operating cycle, whichever is longer).
Conversion of Note Principal and Accrued Interest to Redeemable Convertible Preferred Stock
Represents the conversion of note principal and accrued interest to redeemable convertible preferred stock during the reporting period.
Conversion of note principal and accrued interest to redeemable convertible preferred stock
Conversion of Note Principal and Accrued Interest to Common Stock
Conversion of note principal and accrued interest to common stock
Represents the conversion of note principal and accrued interest to common stock during the reporting period.
Reclassification of Warrant Liability
Reclassification of warrant liability
Represents the reclassification of warrant liability during the reporting period.
Fair Value of Warrants Issued in Connection with Loan Facility
Represents the fair value of warrants issued by the entity in connection with loan facility.
Fair value of warrants issued in connection with loan facilities
Other Assets Equipment Funding [Policy Text Block]
Other Assets-Equipment Funding
Disclosure of accounting policy for other assets-equipment funding obligations of the entity.
Other Assets-Equipment Funding
Other Assets Equipment Funding [Abstract]
Arrangements and Non-arrangement Transactions [Domain]
Aggregate amount agreed to be paid under equipment funding agreement
Represents the aggregate amount committed to be paid under the other assets-equipment funding obligations.
Assets Equipment Funding Aggregate Commitment Amount
Number of monthly installments
Assets Equipment Funding Number of Monthly Installments
Represents the number of monthly installments for the payment of aggregated amount committed to be paid under the other assets-equipment funding obligations..
Period for which the entity is required to make interest-only payments
Represents the period for which the entity is required to make interest-only payments on the debt instrument.
Debt Instrument Term for which Interest Only Payments Required
Debt instrument term
Represents the period for which the debt instrument is going to be in force.
Debt Instrument Term
LIBOR floor (as a percent)
Represents the LIBOR floor rate used in calculating the interest rate applicable to a debt instrument.
Debt Instrument LIBOR Floor
Debt Instrument Interest Rate Increase Due to Payment Default
Increase in interest rate upon the occurrence of a payment default (as a percent)
Represents the increase in rate of interest on outstanding borrowings upon the occurrence of a payment default.
Exercise price of canceled warrants (in dollars per share)
The exercise price of each class of warrants or rights outstanding prior to revision in terms.
Class of Warrant or Right Exercise Price of Warrants or Rights Prior
Maximum borrowings available under debt instrument
Represents the maximum borrowing capacity of a debt instrument.
Debt Instrument Maximum Borrowing Capacity
Current Fiscal Year End Date
Minimum unrestricted cash required to be maintained under the amended credit facility
Represents the minimum amount of unrestricted cash required to be maintained under the terms of the credit facility.
Debt Instrument Covenant Unrestricted Cash Required to be Maintained Minimum
Minimum unrestricted cash proceeds required from an equity event
Represents the minimum unrestricted cash proceeds required from equity for expiration of requirement to maintain unrestricted cash.
Debt Instrument Covenant Minimum Unrestricted Cash Proceeds from Equity Required for Expiration of Maintenance of Unrestricted Cash
Aggregate value of shares which Aspire Capital is committed to purchase under the Purchase Agreement
Represents the aggregate value of shares which the counterparty has agreed to purchase from the entity under the common stock purchase agreement.
Common Stock Purchase Agreement Value of Shares Committed to be Purchased
Debt Instrument Covenant Minimum Monthly Principal Payments to be Made Upon Capital Raise
Minimum monthly payments under the term loan facility
Represents the minimum monthly payments to be made under the term loan facility.
Debt Instrument Total Amendment Fee Payable
Total fee payable
Represents the total amount of amendment fee payable.
Working Capital at Carrying Value
Working capital
Represents the carrying value of working capital as of balance sheet date.
Stock Issued During Period Shares Price Per Share
Represents the offer price per share of the new shares issued during the period
Common stock price per share (in dollars per share)
Represents the gross proceeds from the additional capital contribution to the entity.
Proceeds from Issuance of Common Stock Gross
Gross proceeds from selling shares of common stock
Document Period End Date
Share Based Compensation Arrangement by Share Based Payment Award, Options, Weighted Average Remaining Contractual Term [Abstract]
Weighted Average Remaining Contractual Term in Years
Equity Financing [Abstract]
Equity Financing
Aggregate Intrinsic Value
Share Based Compensation Arrangement by Share Based Payment Award, Options, Intrinsic Value [Abstract]
Common Stock Purchase Agreement Additional Shares that may be Issued
Number of additional shares that the company may elect to sell to Aspire
Represents the number of additional shares which the entity may sell to the counterparty under the common stock purchase agreement.
Minimum closing sale price of common stock required for directing the Regular Purchase of shares (in dollars per share)
Represents the minimum closing sale price of common stock of the entity required for directing the counterparty to a Regular Purchase of shares of the entity under the common stock purchase agreement.
Minimum Closing Stock Price Required for Directing Regular Purchase of Shares
Represents the maximum number of shares which the entity may direct the counterparty to purchase on any trading day under the common stock purchase agreement pursuant to a Regular Purchase.
Maximum Number of Shares that may be Directed to be Purchased per Trading Day Pursuant to Regular Purchase
Maximum number of shares that may be directed to be purchased on any trading day pursuant to a Regular Purchase
Represents the maximum purchase price of shares which the entity may direct the counterparty to purchase at on any trading day under the common stock purchase agreement pursuant to a Regular Purchase.
Maximum Purchase Price of Shares that may be Directed to be Purchased Per Trading Day Pursuant to Regular Purchase
Maximum purchase price of shares that may be directed to be purchased on any trading day pursuant to a Regular Purchase
Shares that may be Directed to be Purchased Pursuant to VWAP Purchase as Maximum Percentage of Volume of Trading on Trading Day Following Regular Purchase
Shares of common stock that may be directed to be purchased as a maximum percentage of aggregate shares of the company's common stock traded on the NASDAQ Global Market on the trading day following the Regular Purchase
Represents the number of shares which the entity may direct the counterparty to purchase under the common stock purchase agreement pursuant to VWAP Purchase expressed as a maximum percentage of volume of trading on a specified stock market on a trading day following the Regular Purchase.
Minimum Trading Price of Shares as Percentage of Closing Price of Shares on Business Day Immediately Preceding VWAP Purchase Date
Minimum trading price as a percentage of the closing price of the company's common stock on the business day immediately preceding the VWAP Purchase date
Represents the price of the shares that may be directed to be purchased pursuant to VWAP Purchase under the common stock purchase agreement expressed as a percentage of the closing price of common stock on the business day immediately preceding the VWAP Purchase date.
Entity [Domain]
Price Per Share of Shares Issued Pursuant to VWAP Purchase as Percentage of Volume Weighted Average Price for Purchase Date
Per share purchase price of common stock sold to Aspire pursuant to a VWAP Purchase as a percentage of the volume weighted average price for such purchase date
Represents the price per share of the shares sold to the counterparty pursuant to VWAP Purchase expressed as a percentage of the volume weighted average price for such purchase date.
Class of Warrant or Right by Expiration Period [Axis]
Represents information pertaining to warrants or rights by expiration period.
Represents the expiration period of warrants or rights.
Class of Warrant or Right Expiration Period [Domain]
2016 through 2020
Represents the warrants or rights, which will expire from 2016 through 2020.
Expiration Period 2016 Through 2020 [Member]
Expiration Period 2016 [Member]
2016
Represents the warrants or rights, which will expire in 2016.
Common stock warrants expiring in 2016
Represents information pertaining to Severance Agreement entered with Jane H. Hollingsworth by the entity on July 25, 2012.
Severance Agreement [Member]
Severance Agreement
Consulting Agreement [Member]
Consulting Agreement
Represents information pertaining to Consulting Agreement entered with Jane H. Hollingsworth by the entity on July 25, 2012.
Employment Agreement [Member]
Employment Agreement
Represents information pertaining to Employment Agreement entered with Armando Anido by the entity on July 25, 2012.
Modification of Term Loan Debt Covenant Agreement [Member]
Modification of term loan debt covenant
Represents information pertaining to the modification of the term loan debt covenant agreement entered into by the entity.
Amendment to Term Loan Facility
Represents information pertaining to the amendment of term loan facility of the entity.
Amendment to Term Loan Facility [Member]
Period for which Continued Salary Receivable to Individual from Separation Date
Period for which continued salary receivable to individual following the Separation Date
Represents the period for which continued salary receivable to an individual from the reporting entity following the separation date under the agreement.
Severance Costs to be Paid
Estimated severance expense
Represents the amount of severance payments to be paid by the reporting entity to individuals under the agreement.
Accrued Separation and Accrued but Unused Vacation Owed Expense
Accrued separation payments as well as accrued but unused vacation owed to the separated employees
Represents the amount of accrued separation payments as well as accrued but unused vacation owed to the separated employees.
Maximum Period of Commencement from Separation Date for Severance Payments in Bi Weekly Installments
Maximum period of commencement from separation date for severance payments in bi weekly installments
Represents the maximum period of commencement from separation date for severance payments in bi weekly installments to individuals by the reporting entity under the agreement.
Maximum Reimbursement for Professional Fess Incurred by Individual under Agreements
Maximum reimbursement for professional fees incurred by individual in execution of agreements
Represents the maximum amount of reimbursement for professional fees incurred by an individual in execution of the agreements.
Monthly retainer amount for limited continued service provided by an individual
Represents the monthly retainer amount provided by reporting entity for limited continued service provided by an individual under the agreement.
Monthly Retainer Amount for Limited Continued Service Provided by Individual
Share Based Compensation Arrangement by Share Based Payment Award, Options, Estimated Aggregate Fair Value
Estimated aggregate fair value
Represents the amount of estimated aggregate fair value of initial options.
Non Cash Expense Related to Modification of Equity Awards
Non-Cash expense related to modification of previously awarded equity-based awards
Represents the amount of non-cash expense related to the modification of previously awarded equity-based awards.
Represents the amount of annual base salary to be paid by the reporting entity to an individual under the agreement.
Annual Base Salary to be Paid
Initial annual base salary to be paid
Bonus Amount Eligible to Receive by Individual Subject to if Entity Raises Specified Amount of Gross Proceeds from Equity Financings
Bonus amount eligible to receive by an individual, if the Company raises a specified amount of gross proceeds from equity financings
Represents the bonus amount eligible to receive by an individual, if the entity raises a specified amount of gross proceeds from equity financings under the agreement.
Bonus Eligibility of Individual as Percentage of Individual Current Base Salary
Bonus eligibility of individual as a percentage of individual current base salary
Represents the bonus eligibility of individual as a percentage of individual current base salary under the agreement.
Vesting rights of initial option (as a percent)
Share Based Compensation Arrangements by Share Based Payment Award Vesting Rights Percentage One Year from Date of Grant
Represents the description of award terms as to how many shares or portion of an award after the date of grant are no longer contingent on satisfaction of either a service condition, market condition or a performance condition, thereby giving the employee the legal right to convert the award to shares, shown as a percentage.
Represents the period of time, from the grant date until the time at which the share-based award expires.
Share Based Compensation Arrangements by Share Based Payment Award, Expiration Term
Term of award
Share Based Compensation Arrangements by Share Based Payment Award, Award Vesting Period from Date of Grant
Period of vesting of awards from the date of grant
Represents the starting period of vesting of awards from the date of grant.
Severance agreement, payment period
Represents the period of payment of under severance agreement.
Period of Payment under Severance Agreement
Maximum monthly consulting services to be provided to the Company
Represents the maximum period for which consultancy services to be provided per month.
Maximum Monthly Retainer Period of Limited Continued Service Provided by Individual
Required notice period for termination of agreement
Represents the required notice period for termination of an agreement by a related party.
Required Notice Period for Termination of Agreement
Share Based Compensation Arrangement by Share Based Payment Award, Number of Quarterly Installments Vesting of Award
Number of equal quarterly installments for vesting of award
Represents the number of equal quarterly installments over which the awards vest, from the starting period of vesting of the awards from the date of grant.
Share Based Compensation Arrangement by Share Based Payment Award, Accelerated Vesting Number of Options
Number of shares for accelerated vesting
Represents the number of shares for accelerated vesting upon achievement of milestones.
Share Based Compensation Arrangement by Share Based Payment Award, Percentage of Options, Granted for Equity Financing Transaction
Represents the percentage of common shares available to purchase based on gross common shares issued by the Company in connection with equity financing transaction.
Additional shares available to purchase upon completion of equity financing transaction (as a percent)
Share Based Compensation Arrangement by Share Based Payment Award, Period of Options, Granted for Equity Financing Transaction
Represents the period of common shares available to purchase based on gross common shares issued by the Company in connection with equity financing transaction.
Period of additional shares available to purchase upon completion of equity financing transaction
Debt Instrument Amendment Fee Payable Upon Closing of Equity Financing
Amendment fee payable upon closing of the October 2012 Financing
Represents the amount of amendment fee payable upon closing of an additional capital raise.
Debt Instrument Additional Amendment Fee Payable in Final Interest Payment
Additional fee payable in final interest payment
Represents the amount of additional amendment fee payable in final interest payment.
Number of shares to be purchased against each warrant
Represents the number of shares of common stock available for purchase via warrants.
Class of Warrant or Right Number of Shares Common Stock Available for Purchase by Rights Holder
Stock Issued During Period Shares New Issues Equivalent to Shares of Preferred Stock
Number of shares of preferred stock equivalent to shares issued by the entity
Represents the number of shares of preferred stock equivalent to number of shares issued by the entity.
Equivalent number of shares of preferred stock included in units issued by the entity
Stock Issued During Period Shares New Issues Equivalent to Number of Warrants of Common Stock
Number of warrants equivalent to shares issued by the entity
Represents the number of warrants to purchase common stock equivalent to number of shares issued by the entity.
Increased Preferred Stock Dividend Rate Percentage Upon Non Approval by Authority
Dividend rate on Series A preferred stock if FDA does not approve Zecuity by June 30, 2013, calculated as 12% per 1/1000 share (as a percent per share)
Represents the increase in preferred stock dividend rate, upon non-approval by the United States Food and Drug Administration.
Convertible Preferred Stock Conversion Price
Conversion price, calculated as $2.00 per 1/1000 share (in dollars per share)
The price per share of the conversion feature embedded in the preferred stock.
Convertible Preferred Stock Value Divided by Effective Conversion Price to Determine Number of Shares of Common Stock
Numerator used to calculate the number of shares of common stock receivable upon conversion, calculated as $2.00 per 1/1000 share (in dollars per share)
Represents the value that is divided by the effective conversion price to determine the number of common stock shares to be received upon conversion.
Class of Warrant or Right Term
Represents the term of warrants.
Term of warrants
Class of Warrant or Right Number of Months over which Warrants Become Exercisable Following Date of Issuance
Term that warrants become exercisable from the date of issuance.
Represents the period over which warrants remain exercisable from the date of issuance.
Period of time after issuance when warrants become exercisable
Class of Warrant or Right Number of Securities Cancelled which were Previously Called by Warrants or Rights
Number of common stock warrants cancelled, which was previously issued (in shares)
Represents the number of common stock warrants cancelled, which were previously issued.
Number of Employees Reduced Expressed as Percentage of Total Workforce
Reduction in workforce (as a percent)
Represents the number of employees reduced, expressed as a percentage of total workforce.
Summary of Significant Accounting Policies
Number of Full Time Positions Reduced
Number of full-time positions reduced
Represents the number of full-time positions reduced.
Accrued Research and Development Expense Current
Accrued research and development expenses
Carrying value, as of the balance sheet date, of obligations incurred through that date and payable for research and development expenses. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle, if longer).
Entity Well-known Seasoned Issuer
Accrued interest and other
Sum of the carrying values, as of the balance sheet date, of (a) interest payable on all forms of debt, including trade payables, that has been incurred, and (b) current liabilities not separately disclosed in the balance sheet. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle, if longer).
Interest Payable and Other Accrued Liabilities Current
Entity Voluntary Filers
Computer Equipment and Software [Member]
Computer equipment and software
Represents the long lived, depreciable assets such as computers and that are used in the creation, maintenance and utilization of information systems and purchased software applications.
Computer equipment including software
Entity Current Reporting Status
Lab Equipment [Member]
Lab equipment
Represents information pertaining to lab equipment.
Laboratory equipment
Entity Filer Category
University of Pennsylvania [Member]
Penn
Represents the University of Pennsylvania, with which the entity has entered into a patent license agreement.
Entity Public Float
Evonik Industries AG Inc [Member]
Evonik
Represents Evonik Industries AG, Inc., successor to SurModics Pharmaceuticals, Inc., with which the entity has entered into a license agreement.
Entity Registrant Name
Represents the annual amount required to be committed by the entity under the collaborative arrangement unit 1 the first commercial sale of the first licensed product.
Amount required to be committed under agreement
Collaborative Arrangements Annual Amount Required to be Committed
Entity Central Index Key
Collaborative Arrangement Annual License Maintenance Payments
Annual license maintenance payments
Represents the amount of annual license maintenance payments to the third party until the first commercial sale of the first licensed product.
Collaborative Arrangement Milestone Payments Payable
Milestone payments payable
Represents the amount payable by the entity upon the achievement of specified milestones.
Collaborative Arrangement Patent Prosecution Costs
Patent prosecution costs
Represents the patent prosecution costs incurred by the entity under the collaborative arrangement.
Equipment Funding Agreement [Abstract]
Equipment Funding Agreement
Entity Common Stock, Shares Outstanding
Represents the maximum percentage of compensation that can be contributed by employees to the defined contribution plan.
Defined Contribution Plan Employee Contribution as Percentage of Compensation Maximum
Maximum percentage of salary that eligible employees can contribute
Schedule of Operating Losses and Tax Credit Carryforwards [Table Text Block]
Tabular disclosure of net operating losses and tax credit carryforwards.
Summary of carryforwards of net operating losses and tax credits
Research and Development Tax Credits Sold
Pennsylvania research and development tax credits sold
Represents the amount of research and development tax credit sold by the entity.
Debt Instrument Number of Officers to whom Debt is Issued
Number of officers to whom debt is issued
Represents the number of officers to whom debt has been issued by the entity.
Debt Instrument Conversion Obligation Conversion Price as Percentage of Common Stock Offering Price
Conversion price as a percentage of common stock offering price
Represents the conversion price of debt instrument, expressed as a percentage of the offering price of common stock of the entity's IPO.
Stock Issued During Period Shares Conversion of Convertible Notes to Common Stock
Conversion of convertible notes and accrued interest into common stock (in shares)
Number of common shares issued during the period as a result of the conversion of convertible securities.
Debt Instrument Number of Loan Agreements
Number of loan agreements
Represents the number of loan agreements entered into by the entity.
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Expenses
Employee [Member]
Employee
Represents information pertaining to the employee of the entity.
Non Employee [Member]
Nonemployee
Represents information pertaining to the nonemployee of the entity.
Performance Based Stock Options [Member]
Performance-based stock options
Contract that gives the holder the right, but not the obligation, either to purchase or to sell a certain number of shares of stock at a predetermined price for a specified period of time on meeting certain performance targets.
Share Based Compensation Arrangement by Share Based Payment Award, Number of in the Money Options
Number of in-the-money options outstanding (in shares)
Represents the number of in-the-money options.
Exercise Price Range from Dollars 0.80 to 2.11 [Member]
$0.80 - $2.11
Represents the range of exercise price from 0.80 dollars to 2.11 dollars.
Exercise Price Range from Dollars 2.12 to 3.42 [Member]
$2.12 - $3.42
Represents the range of exercise price from 2.12 dollars to 3.42 dollars.
Represents the range of exercise price from 3.43 dollars to 4.74 dollars.
Exercise Price Range from Dollars 3.43 to 4.74 [Member]
$3.43 - $4.74
Exercise Price Range from Dollars 4.75 to 6.06 [Member]
Represents the range of exercise price from 4.75 dollars to 6.06 dollars.
$4.75 - $6.06
Exercise Price Range from Dollars 6.07 to 7.37 [Member]
$6.07 - $7.37
Represents the range of exercise price from 6.07 dollars to 7.37 dollars.
Exercise Price Range from Dollars 7.38 to 8.69 [Member]
$7.38 - $8.69
Represents the range of exercise price from 7.38 dollars to 8.69 dollars.
Document Fiscal Year Focus
Exercise Price Range from Dollars 8.70 to 10.00 [Member]
$8.70 - $10.00
Represents the range of exercise price from 8.70 dollars to 10.00 dollars.
Document Fiscal Period Focus
Share Based Compensation Shares Authorized under Stock Option Plans Exercise Price Range Outstanding Options [Abstract]
Options outstanding
Share Based Compensation Shares Authorized under Stock Option Plans Exercise Price Range Exercisable Options [Abstract]
Options exercisable
Initial Public Offering [Abstract]
Initial Public Offering
Expiration Period 2017 [Member]
2017
Represents the warrants or rights, which will expire in 2017.
Conversion of convertible notes and accrued interest into Series A redeemable convertible preferred stock
Stock Issued During Period Value Conversion of Convertible Notes to Series A Preferred Stock Net of Adjustments
The net amount of series A redeemable convertible preferred stock issued during the period upon conversion of convertible securities, net of adjustments.
Stock Issued During Period Shares Conversion of Convertible Notes to Series A Preferred Stock
Conversion of convertible notes and accrued interest into Series A redeemable convertible preferred stock (in shares)
Number of series A redeemable convertible preferred stock issued during the period as a result of the conversion of convertible securities.
Temporary Equity Stock Issued During Period Shares New Issues
Sale of Series A redeemable convertible preferred stock at $0.93 per share for the year 2006, 2007, and 2008 and net of expenses of $267 and $20 for the year 2006 and 2007, respectively (in shares)
The number of securities classified as temporary equity that have been sold (or granted) to the entity's shareholders.
Temporary Equity Stock Issued During Period Value Series Second in Year
Sale of Series B redeemable convertible preferred stock at $0.93 per share for the years 2008 and 2009 and net of expenses of $304 and $16 for the years 2008 and 2009, respectively
Value of new stock classified as temporary equity issued during the period.
Sale of Series B redeemable convertible preferred stock at $0.93 per share for the years 2008 and 2009 and net of expenses of $304 and $16 for the years 2008 and 2009, respectively (in shares)
The number of securities classified as temporary equity that have been sold (or granted) to the entity's shareholders when there is a second issuance during a reporting period.
Temporary Equity Shares Issued Series Second in Year
Conversion of convertible notes and accrued interest into Series B redeemable convertible preferred stock
The net amount of series B redeemable convertible preferred stock issued during the period upon conversion of convertible securities, net of adjustments.
Stock Issued During Period Value Conversion of Convertible Notes to Series B Preferred Stock Net of Adjustments
Stock Issued During Period Shares Conversion of Convertible Notes to Series B Preferred Stock
Conversion of convertible notes and accrued interest into Series B redeemable convertible preferred stock (in shares)
Number of series B redeemable convertible preferred stock issued during the period as a result of the conversion of convertible securities.
Legal Entity [Axis]
Stock Issued During Period Value Conversion of Convertible Notes to Common Stock Net of Adjustments
Conversion of convertible notes and accrued interest into common stock
The net amount of common stock issued during the period upon conversion of convertible securities, net of adjustments.
Document Type
Value of warrants reclassified to purchase common stock.
Adjustments to Additional Paid in Capital Reclassification of Warrants
Reclassification of warrants to purchase common stock
Temporary Equity Stock Issuance Cost
Sale of Series A redeemable convertible preferred stock, expenses (in dollars)
Costs incurred directly with the issuance of redeemable convertible preferred stock during the reporting period.
Temporary Equity Stock Issuance Cost Second in Year
Sale of Series B redeemable convertible preferred stock, expenses (in dollars)
Costs incurred directly with the issuance of redeemable convertible preferred stock when there is a second issuance during a reporting period.
Office Equipment and Furniture [Member]
Tangible personal property used in an office setting. Along with equipment commonly used in offices and stores that have no permanent connection to the structure of a building or utilities. Examples include, but are not limited to, desks, chairs, tables, and bookcases.
Office equipment and furniture
Grants Awarded
Represents the amount of money awarded to an entity to carry out a specific purpose as provided in grant agreements.
Grant awarded
Aspire Capital Fund LLC [Member]
Aspire Capital
Represents Aspire Capital Fund, LLC.
Threshold of Gross Proceeds from Financing or Licensing or Partnership or Other Corporate Collaboration Triggering Conversion to Common Stock
The gross proceeds threshold from financing, licensing, partnership or other corporate collaboration triggering the conversion to common stock
The gross proceeds threshold from financing, licensing, partnership or other corporate collaboration triggering the conversion to common stock.
Term Loan 2012 [Member]
2012 Term Loan
Represents information pertaining to the 2012 Term Loans.
Debt Instrument Origination Fee in Shares
Origination fee (in shares)
Represents the number of shares issued to third parties in connection with debt origination.
Debt Instrument Fee Payable In Final Payment
Final payment fee required to be paid
Represents the amount of fee payable in final payment.
Debt Instrument Fee Payable in Final Payment as Percentage of Original Principal Amount
Final payment fee required to be paid as percentage of original principal amount
Represents the fee payable in final payment as a percentage of the original principal amount.
Deemed Dividend Convertible Beneficial Conversion Feature
Deemed dividend
Represents the amount of deemed dividend recorded as a result of warrants and preferred stock being issued at discount.
Deemed dividend-beneficial conversion feature
Deemed dividend-beneficial conversion feature
Deemed dividend
Change in Fair Value of Warrants
Increase in fair value of warrants
Represents the increase (decrease) in the fair value of the warrant liability during the period.
Change in fair value of warrants
Increase in fair value of warrants
Transaction Fees
Transaction Fees
Represents the transaction fees recorded as a reduction of the allocation to preferred stock.
Warrant One Expiration Period 2017 [Member]
2017
Represents the warrants or rights one, which will expire in 2017.
Warrant Two Expiration Period 2017 [Member]
2017
Represents the warrants or rights two, which will expire in 2017.
Fair Value of Warrants Issued in Connection with Equity Financing and Loan Modification
Fair value of warrants issued in connection with equity financing and loan modification
Represents the fair value of warrants issued by the entity in connection with equity financing and loan modification.
Warrant liability
Nonqualified Stock Options [Member]
Non-qualified stock options
Represents non-qualified stock options as awarded by the entity to its employees as a form of incentive compensation.
Omnibus Incentive Compensation Plan 2010 [Member]
The 2010 Plan
Represents information pertaining to the 2010 Omnibus Incentive Compensation Plan of the entity.
Share Based Compensation Arrangement by Share Based Payment Award Number of Options Exchanged for Each Share of Awards other than Options
Number of options exchanged for each share of awards other than options
Represents the number of stock options exchanged for each share of awards other than options.
Restricted Stock and Restricted Stock Units RSU [Member]
Restricted stock and restricted stock units
Represents information pertaining to restricted stock and restricted stock units.
Vesting Rights Percentage
Vesting percentage
Description of award terms as to how many shares or portion of an award are no longer contingent on satisfaction of either a service condition, market condition or a performance condition, thereby giving the employee the legal right to convert the award to shares, shown as a percentage.
Share Based Compensation Arrangement by Share Based Payment Award Vesting in Number of Equal Quarterly Installments
Awards vesting in number of equal quarterly installments
Represents the number of equal quarterly installments in which awards will vest.
Payments of Interest on Debt Extinguishment
Cash paid for interest on debt extinguishment
Represents the cash outflow resulting from the interest pertaining to an early extinguishment of debt.
Stock Issued During Period Value Loan Agreement
Common shares issued pursuant to loan agreement
Represents value of stock issued in respect of origination fees paid for loan agreement during the period.
Stock Issued During Period Shares Loan Agreement
Common shares issued pursuant to loan agreement (in shares)
Represents number of shares issued pursuant to origination fees of loan agreement.
Accounts Payable, Current
Accounts payable
Stock Issuance Costs
Sale of stock, expenses (in dollars)
Represents the amount of stock issuance costs.
Transaction fees
Accrued professional fees
Accrued Professional Fees, Current
Accrued Liabilities, Current
Accrued expenses
Accrued expenses
Less accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Additional Paid in Capital, Common Stock
Additional paid-in capital
Additional Paid-in Capital
Additional Paid-in Capital [Member]
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Sale of common stock, expenses (in dollars)
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Beneficial conversion feature related to convertible notes and warrant agreements
Adjustments to Additional Paid in Capital, Convertible Debt with Conversion Feature
Fair value of warrants issued in connection with loan facility
Adjustments to Additional Paid in Capital, Warrant Issued
Allocated Share-based Compensation Expense
Stock-based compensation expense
Stock-based compensation expense (in dollars)
Amortization of Financing Costs
Noncash interest expense
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Potentially dilutive securities excluded from the computations of diluted weighted-average shares outstanding because of anti-dilutive effect
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Net Loss per Common Share
Antidilutive Securities, Name [Domain]
Antidilutive Securities [Axis]
Assets, Current [Abstract]
Current assets:
Assets [Abstract]
ASSETS
Assets, Current
Total current assets
Assets
Total assets
Assets, Fair Value Disclosure [Abstract]
Assets
Basis of Presentation and Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Cash equivalents
Cash Equivalents, at Carrying Value
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and cash equivalents, beginning of period
Cash and cash equivalents, end of period
Cash Equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash Equivalents
Cash and Cash Equivalents [Abstract]
Cash and Cash Equivalents, Fair Value Disclosure
Fair value of cash equivalents
Cash equivalents
Chief Executive Officer and Director
Chief Executive Officer [Member]
Former Chief Executive officer
Class of Warrant or Right [Table]
Class of Warrant or Right [Line Items]
Warrants
Class of Stock [Line Items]
Equity Financings
Capital Structure and Equity Financings
Class of Warrant or Right, Exercise Price of Warrants or Rights
Exercise price of warrants issued to lender (in dollars per share)
Exercise Price (in dollars per share)
Exercise price (in dollars per share)
Class of Stock [Domain]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Warrants issued to lender (in shares)
Warrants to purchase common stock, number of shares
Number of shares of preferred stock included in each unit
Number of warrants to purchase common stock
License agreements
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
License Agreements
Collaborative Arrangement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Domain]
Collaborative Arrangements and Non-collaborative Arrangements [Axis]
Commitments and Contingencies Disclosure [Text Block]
Commitments
Commitments
Commitments (note 9)
Commitments and Contingencies
Common Stock [Member]
Common Stock
Common Stock, Shares, Outstanding
Common stock, outstanding shares
Common Stock, Value, Issued
Common stock, $0.001 par value; authorized 90,000,000 shares; issued and outstanding 20,023,949 and 14,748,582 shares at December 31, 2012 and December 31, 2011, respectively
Common Stock, Shares, Issued
Common stock, issued shares
Issuance of common stock to initial stockholders
Common Stock, Dividends, Per Share, Declared
Common Stock, Par or Stated Value Per Share
Common stock, par value (in dollars per share)
Par value of common stock (in dollars per share)
Common stock, authorized shares
Common Stock, Shares Authorized
401(k) Profit Sharing Plan
Significant portions of the deferred tax assets
Components of Deferred Tax Assets [Abstract]
Construction in progress
Construction in Progress [Member]
Number of shares converted
Conversion of Stock, Shares Converted
Conversion of preferred stock plus accrued dividends to common stock
Conversion of Stock, Amount Converted
Shares of convertible preferred stock (common stock equivalent)
Convertible Preferred Stock [Member]
Convertible Preferred Stock
Convertible Notes
Convertible Notes Payable [Member]
Reference rate
Debt Instrument, Description of Variable Rate Basis
Debt
Debt Instrument [Line Items]
Schedule of Long-term Debt Instruments [Table]
Debt Disclosure [Text Block]
Debt
Debt
Debt Instrument, Basis Spread on Variable Rate
Interest rate added to the reference rate (as a percent)
Repayment of debt
Debt Instrument, Decrease, Repayments
Minimum interest rate (as a percent)
Debt Instrument, Interest Rate, Stated Percentage Rate Range, Minimum
Aggregate amount financed
Debt Instrument, Increase, Additional Borrowings
Debt Instrument, Interest Rate at Period End
Interest rate at period end (as a percent)
Interest rate on debt instrument (as a percent)
Debt Instrument, Interest Rate, Stated Percentage
Depreciation and amortization
Deferred Tax Assets, Property, Plant and Equipment
Title of Individual [Axis]
Deferred tax assets
Deferred Tax Assets, Net of Valuation Allowance
Gross deferred tax asset
Deferred Tax Assets, Gross
Net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards
Research and development credit
Deferred Tax Assets, Tax Credit Carryforwards, Research
Other temporary differences
Deferred Tax Assets, Other
Deferred tax assets valuation allowance
Deferred Tax Assets, Valuation Allowance
Maximum matching contributions as a percentage of employee's biweekly contribution
Defined Contribution Plan, Maximum Annual Contribution Per Employee, Percent
Percentage of the company's contribution that vested upon the contribution date
Defined Contribution Plan, Employers Matching Contribution, Annual Vesting Percentage
Matching contributions sponsored by the company
Defined Contribution Plan, Cost Recognized
Depreciation, Depletion and Amortization
Depreciation expense
Depreciation and amortization expense
Development Stage Enterprise General Disclosures [Text Block]
Development-Stage Risks and Liquidity
Development Stage Enterprise, Deficit Accumulated During Development Stage
Deficit accumulated during the development stage
Accumulated deficit during development-stage
Development-Stage Risks and Liquidity
Director [Member]
Directors
Disclosure of Compensation Related Costs, Share-based Payments [Text Block]
Stock-Based Compensation
Stock-Based Compensation
Deemed dividend on preferred shares
Dividends, Preferred Stock
Basic and diluted net loss per common share (in dollars per share)
Earnings Per Share, Basic and Diluted
Earnings Per Share, Policy [Policy Text Block]
Net Loss Per Common Share
Reconciliation of the statutory U.S. federal rate to the effective tax rate
Effective Income Tax Rate, Continuing Operations, Tax Rate Reconciliation [Abstract]
Effective income tax rate (as a percent)
Effective Income Tax Rate, Continuing Operations
U.S. federal statutory income tax rate (as a percent)
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate
State taxes, net of federal benefit (as a percent)
Effective Income Tax Rate Reconciliation, State and Local Income Taxes
Change in valuation allowance (as a percent)
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance
Other (as a percent)
Effective Income Tax Rate Reconciliation, Other Adjustments
Accrued compensation and benefits
Employee-related Liabilities, Current
Employee Service Share-based Compensation, Nonvested Awards, Total Compensation Cost Not yet Recognized, Period for Recognition
Remaining vesting period of awards
Expected period of recognition of unrecognized compensation expense
Employee Service Share-based Compensation, Allocation of Recognized Period Costs, Report Line [Domain]
Employee Service Share-based Compensation, Nonvested Awards, Total Compensation Cost Not yet Recognized, Stock Options
Unrecognized compensation expense related to unvested awards
Unrecognized compensation expense related to unvested restricted stock
Employee Service Share-based Compensation, Nonvested Awards, Total Compensation Cost Not yet Recognized, Share-based Awards Other than Options
Equity [Abstract]
Equity financing
Equity Component [Domain]
Total
Estimate of Fair Value, Fair Value Disclosure [Member]
Executive officers
Executive Officer [Member]
Measurement Frequency [Axis]
Fair Value, Hierarchy [Axis]
Liability Class [Axis]
Recurring
Fair Value, Measurements, Recurring [Member]
Fair Value, Measurement with Unobservable Inputs Reconciliations, Recurring Basis, Liability Value
Balance at the beginning of the period
Balance at the end of the period
Fair Value, Measurement Frequency [Domain]
Fair Value Measurements, Recurring and Nonrecurring [Table]
Fair Value by Liability Class [Domain]
Fair Value, Measurements, Fair Value Hierarchy [Domain]
Issuance of warrants
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Issues
Fair Value of Financial Instruments
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Disclosures [Abstract]
Fair Value of Financial Instruments
Fair Value of Financial Instruments, Policy [Policy Text Block]
Fair Value of Financial Instruments
Significant Unobservable Inputs (Level 3)
Fair Value, Inputs, Level 3 [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1)
Fair Value, Inputs, Level 1 [Member]
Significant Other Observable Inputs (Level 2)
Fair Value, Inputs, Level 2 [Member]
Change in fair value of warrant liability
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings
Reconciliation of warrant liability measured at fair value on a recurring basis using unobservable inputs (Level 3)
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Schedule of reconciliation of warrant liability measured at fair value on a recurring basis using unobservable inputs (Level 3)
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Reconciliation of warrant liability measured at fair value on a recurring basis using unobservable inputs (Level 3)
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Gain (Loss) on Disposition of Assets
Loss on asset disposal
Interest not previously accrued
Gains (Losses) on Extinguishment of Debt, before Write off of Deferred Debt Issuance Cost
Loss on debt extinguishment
Gains (Losses) on Extinguishment of Debt
Loss on debt extinguishment
Loss on debt extinguishment
Instrument Type [Domain]
Instrument [Axis]
Statements of Operations
Income Taxes
Income Tax Disclosure [Text Block]
Income Taxes
Income Tax Authority [Axis]
Income Tax Authority [Domain]
Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Extraordinary Items, Noncontrolling Interest
Loss before tax benefit
Income Tax Expense (Benefit)
Income tax benefit
Income Taxes
Income Tax, Policy [Policy Text Block]
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accrued Liabilities
Accrued expenses
Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other assets
Increase (Decrease) in Stockholders' Equity
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Interest Expense
Interest expense
Interest expense, net
Interest Income (Expense), Nonoperating, Net
Interest Paid
Cash paid for interest
Federal
Internal Revenue Service (IRS) [Member]
Investment Income, Interest
Interest income
Long-term Debt, Type [Domain]
Long-term Debt, Type [Axis]
Leasehold improvements
Leasehold Improvements [Member]
Leases
Leases, Operating [Abstract]
Liabilities, Current
Total current liabilities
Liabilities Assumed
Financing arrangement with third party vendors
Liabilities, Current [Abstract]
Current liabilities:
Liabilities
Total liabilities
Liabilities and Equity [Abstract]
LIABILITIES AND STOCKHOLDERS' EQUITY
Liabilities:
Liabilities, Fair Value Disclosure [Abstract]
Liabilities and Equity
Total liabilities and stockholders' equity
Annual license fees
License Costs
Long-term Debt
Carrying amount of long-term debt
Total
Long-term Debt, Current Maturities
Current portion of long-term debt
Current portion of long-term debt
Long-term Debt, Excluding Current Maturities
Long-term debt
Maximum [Member]
Maximum
Minimum [Member]
Minimum
Nature of Operations [Text Block]
Background
Cash flows from financing activities:
Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract]
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities, Continuing Operations
Cash flows from operating activities:
Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract]
Net increase (decrease) in cash and cash equivalents
Net Cash Provided by (Used in) Continuing Operations
Net cash used in investing activities
Net Cash Provided by (Used in) Investing Activities, Continuing Operations
Net Income (Loss) Available to Common Stockholders, Basic
Net loss applicable to shareholders
Net loss
Net loss applicable to common stockholders
Net cash provided by financing activities
Net Cash Provided by (Used in) Financing Activities, Continuing Operations
Cash flows from investing activities:
Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract]
Net loss
Net loss
Net Income (Loss) Attributable to Parent
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Issued Accounting Pronouncements
Summary of New Accounting Pronouncements and Changes in Accounting Principles
Noncash Investing and Financing Items [Abstract]
Noncash investing and financing activities:
Number of businesses in which the company operates
Number of Operating Segments
Future minimum lease payments
Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract]
Operating Expenses [Abstract]
Operating expenses:
Operating Expenses
Total operating expenses
Operating expenses
Net operating losses
Operating Loss Carryforwards
Rent expense
Operating Leases, Rent Expense, Net
Operating Income (Loss)
Loss from operations
2015
Operating Leases, Future Minimum Payments, Due in Three Years
2014
Operating Leases, Future Minimum Payments, Due in Two Years
2013
Operating Leases, Future Minimum Payments Due, Next Twelve Months
Total
Operating Leases, Future Minimum Payments Due
Background
Other Assets, Noncurrent
Other assets
Other long-term liabilities
Other Liabilities, Noncurrent
Accrued Expenses
Payments of Debt Issuance Costs
Payment of debt issuance costs
Origination fee paid in cash
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Payments to Acquire Other Productive Assets
Payments under equipment funding agreement
Payments made under the equipment funding agreement
Payments to Acquire in Process Research and Development
Purchase of in-process research and development
401(k) Profit Sharing Plan
Pension and Other Postretirement Benefits Disclosure [Text Block]
Plan Name [Domain]
Plan Name [Axis]
Preferred Stock, Value, Issued
Preferred stock, $0.001 par value; authorized 10,000,000 shares; issued and outstanding 8,804 and 0 at December 31, 2012 and December 31, 2011, respectively (liquidation value of $17,608 at December 31, 2012)
Preferred Stock, Shares Authorized
Preferred stock, authorized shares
Preferred Stock, Dividend Rate, Percentage
Dividend rate on Series A preferred stock, calculated as 8% per 1/1000 share (as a percent per share)
Preferred Stock, Shares Issued
Preferred stock, issued shares
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value (in dollars per share)
Par value of preferred stock (in dollars per share)
Preferred stock, liquidation value (in dollars)
Preferred Stock, Liquidation Preference, Value
Preferred Stock, Shares Outstanding
Preferred stock, outstanding shares
Redeemable Convertible Preferred Stock
Preferred Stock [Member]
Preferred Stock
Prepaid Expense and Other Assets, Current
Prepaid expenses and other
Proceeds from Issuance of Debt
Proceeds from issuance of debt
Proceeds from Convertible Debt
Proceeds from convertible notes
Cash proceeds
Proceeds from Loan Originations
Loan proceeds
Proceeds from Issuance of Common Stock
Proceeds from sale of common stock, net
Net proceeds resulting from sale of securities under the October 2012 Financing
Proceeds from Issuance of Redeemable Convertible Preferred Stock
Proceeds from sale of preferred stock, net
Net proceeds from transaction
Proceeds from Sale of Available-for-sale Securities
Net proceeds resulting from sale of securities under the October 2012 Financing
Estimated useful life
Property, Plant and Equipment, Useful Life
Property, Plant and Equipment, Type [Domain]
Property and Equipment
Property and Equipment
Property, Plant and Equipment, Policy [Policy Text Block]
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Property and equipment
Property, Plant and Equipment [Line Items]
Property and Equipment
Property and equipment, gross
Property, Plant and Equipment, Gross
Schedule of property and equipment
Property, Plant and Equipment [Table Text Block]
Property, Plant and Equipment, Type [Axis]
Property and Equipment
Property, Plant and Equipment Disclosure [Text Block]
Quarterly Financial Information (unaudited)
Quarterly Financial Information [Text Block]
Quarterly Financial Information (unaudited)
Range [Axis]
Range [Domain]
Repayments of Debt
Repayment of debt
Research and Development Expense (Excluding Acquired in Process Cost)
Research and development
Research and development credits
Research Tax Credit Carryforward [Member]
Research and development
Research and Development Expense [Member]
Research and Development and In-Process Research and Development
Research and Development Expense, Policy [Policy Text Block]
Research and Development in Process
Acquired in-process research and development
Restricted Stock [Member]
Shares of unvested restricted stock
Restricted stock
Deficit Accumulated During the Development Stage
Retained Earnings [Member]
Revenue from Grants
Grant revenue
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value
Exercisable at the end of the period (in dollars)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Vested and expected to vest at the end of the period
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term
Expected life
Weighted average remaining contractual term
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Exercisable Options, Weighted Average Remaining Contractual Term
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Exercisable at the end of the period
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Outstanding at the end of the period
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Outstanding Options, Weighted Average Remaining Contractual Term
Weighted average remaining contractual term
Scenario, Unspecified [Domain]
Schedule of financial assets and liability measured at fair value on a recurring basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of Nonvested Share Activity [Table Text Block]
Schedule of aggregate restricted stock activity
Schedule of aggregate stock option activity
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of weighted average assumptions used in determining the fair value of stock options
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of potentially dilutive securities excluded from the computations of diluted weighted-average shares outstanding
Schedule of reconciliation of the statutory U.S. federal rate to the Company's effective tax rate
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of accrued expenses
Schedule of Accrued Liabilities [Table Text Block]
Schedule of future minimum lease payments
Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block]
Summary of unaudited quarterly results of operations
Schedule of Quarterly Financial Information [Table Text Block]
Schedule of tax effects of temporary differences that gave rise to significant portions of the deferred tax assets
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule of stock-based compensation expense
Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block]
Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table]
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs, by Report Line [Axis]
Schedule of stock-based compensation expense included in the accompanying statements of operations
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]
Summary of information about stock options outstanding by exercise price range
Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block]
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Schedule of warrants to purchase outstanding common stock
Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Property, Plant and Equipment [Table]
Schedule of Stock by Class [Table]
Secured Debt [Member]
May 2010 Loan Facility
Segment Information
Segment Reporting, Policy [Policy Text Block]
Segment Information
Segment Reporting, Disclosure of Entity's Reportable Segments [Abstract]
Selling, General and Administrative Expense
Selling, general and administrative
Selling, general and administrative
Selling, General and Administrative Expenses [Member]
Series A Preferred Stock [Member]
Series A Preferred Stock
Convertible Preferred Stock
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Number of Shares
Share-based Compensation
Stock-based compensation
Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Cancelled/forfeited (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Granted (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility, high end of range (as a percent)
Forfeited (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility, low end of range (as a percent)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Nonvested shares at the beginning of the period (in dollars per share)
Nonvested shares at the end of the period (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized
Number of additional shares authorized under the plan
Weighted Average Exercise Price
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Roll Forward]
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk free interest rate, high end of range (as a percent)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Roll Forward]
Weighted Average Grant Date Fair Value
Number of shares available for issuance as a percentage of common stock outstanding
Share-based Compensation Arrangement by Share-based Payment Award, Percentage of Outstanding Stock Maximum
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross
Granted (in shares)
Awards granted (in shares)
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Nonvested shares at the beginning of the period
Nonvested shares at the end of the period
Awards Outstanding (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period
Vested (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Forfeited (in dollars per share)
Stock closing price (in dollars per share)
Share Price
Purchase price per unit (in dollars per share)
Common stock price per share (in dollars per share)
Sale of stock, price per share
Granted (in dollars per share)
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period
Granted (in shares)
Issued ( in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk free interest rate, low end of range (as a percent)
Exercised (in dollars per share)
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate (as a percent)
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility (as a percent)
Exercisable at the end of the period (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend yield (as a percent)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Vested (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted-average fair value of stock options granted (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract]
Additional disclosures pertaining to stock options
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number
Exercisable at the end of the period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant
Number of shares available for future grants under the plan
Number of Shares
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized
Number of shares authorized under the plan
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Weighted average assumptions
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period
Cancelled/forfeited (in shares)
Cancelled (in shares)
Number of Options (in shares)
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Number of Exercisable Options
Exercise Price Range [Axis]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Vested and expected to vest at the end of the period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Vested and expected to vest at the end of the period
Stock options outstanding
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Domain]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Outstanding at the beginning of the period (in dollars per share)
Outstanding at the end of the period (in dollars per share)
Outstanding at the end of the period (in dollars)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Vested and expected to vest at the end of the period (in dollars)
Number of Options (in shares)
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Number of Outstanding Options
Exercise price, low end of range (in dollars per share)
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Lower Range Limit
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number
Outstanding at the beginning of the period (in shares)
Outstanding at the end of the period (in shares)
Awards Outstanding (in shares)
Award Type [Domain]
Stock-Based Compensation
Share-based Compensation, Option and Incentive Plans Policy [Policy Text Block]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Vested and expected to vest at the end of the period (in dollars per share)
Exercise price, high end of range (in dollars per share)
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Upper Range Limit
Balance (in shares)
Balance (in shares)
Shares, Issued
Remaining short-term loans
Short-term Debt
Short-term loan agreements
Short-term Debt [Member]
State and Local Jurisdiction [Member]
State
Statement [Table]
Scenario [Axis]
Statement [Line Items]
Statement
Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity (Deficit)
Statements of Cash Flows
Equity Components [Axis]
Balance Sheets
Class of Stock [Axis]
Stock Issued During Period, Shares, Period Increase (Decrease)
Shares underlying outstanding options to purchase common stock
Stock options
Stock Options [Member]
Forfeiture/Cancellation of restricted stock (in shares)
Stock Issued During Period, Shares, Restricted Stock Award, Forfeited
Exercise of stock options
Stock Issued During Period, Value, Stock Options Exercised
Stock Issued During Period, Value, New Issues
Aggregate purchase price of units sold by the entity
Sale of stock, net of expenses
Redeemable Convertible Preferred Stock
Stock Issued During Period, Value, Conversion of Convertible Securities, Net of Adjustments [Abstract]
Stock-based compensation (in shares)
Stock Issued During Period, Shares, Share-based Compensation, Net of Forfeitures
Common shares issued pursuant to conversion of preferred
Stock Issued During Period, Value, Conversion of Convertible Securities, Net of Adjustments
Stock-based compensation
Stock Issued During Period, Value, Share-based Compensation, Net of Forfeitures
Stock Issued During Period, Shares, New Issues
Sale of stock
Number of shares issued
Sale of stock, net of expenses (in shares)
Forfeiture/Cancellation of restricted stock
Stock Issued During Period, Value, Restricted Stock Award, Forfeitures
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period
Exercised (in shares)
Exercise of stock options (in shares)
Common shares issued pursuant to conversion of preferred (in shares)
Stock Issued During Period, Shares, Conversion of Convertible Securities
Number of shares of common stock issued upon conversion
Issuance of restricted stock
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures
Issuance of restricted stock (in shares)
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Stockholders' Equity Attributable to Parent [Abstract]
Stockholders' equity:
Stockholders' Equity Attributable to Parent
Total stockholders' equity
Balance
Balance
Capital Structure and Equity Financings
Capital Structure and Equity Financings
Stockholders' Equity Note Disclosure [Text Block]
Stockholders' Equity, Period Increase (Decrease)
Subsequent Events [Text Block]
Other Events
Other Events
Subsequent Event Type [Domain]
Subsequent Events
Subsequent Event [Line Items]
Subsequent Event Type [Axis]
Subsequent Event [Table]
Subsequent Event
Subsequent Event [Member]
Supplemental Cash Flow Information [Abstract]
Supplemental cash flow disclosures:
Tax credit carryforward
Tax Credit Carryforward, Amount
Tax Credit Carryforward, Name [Domain]
Tax Credit Carryforward [Axis]
Temporary Equity, Shares Outstanding
Redeemable convertible preferred stock, outstanding shares
Sale of Series A redeemable convertible preferred stock at $0.93 per share for the years 2006, 2007, and 2008 and net of expenses of $267 and $20 for the years 2006 and 2007, respectively
Temporary Equity, Stock Issued During Period, Value, New Issues
Redeemable convertible preferred stock, $0.001 par value. Authorized 10,000,000 and 71,745,055 shares at September 30, 2010 and December 31, 2009, respectively; issued and outstanding 53,096,340 shares as of December 31, 2009
Temporary Equity, Carrying Amount, Attributable to Parent
Temporary Equity, Par or Stated Value Per Share
Redeemable convertible preferred stock, par value (in dollars per share)
Temporary Equity, Shares Authorized
Redeemable convertible preferred stock, Authorized shares
Temporary Equity, Accretion to Redemption Value
Accretion of redeemable convertible preferred stock
Accretion of Series A and Series B redeemable convertible preferred stock to redemption value
Temporary Equity, Shares Issued
Redeemable convertible preferred stock, issued shares
Temporary Equity, Accretion to Redemption Value, Adjustment
Accretion of redeemable convertible preferred stock
Title of Individual with Relationship to Entity [Domain]
Type of Arrangement and Non-arrangement Transactions [Axis]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Increase in valuation allowance
Valuation Allowance, Deferred Tax Asset, Change in Amount
Warrant [Member]
Shares underlying outstanding warrants to purchase common stock
Warrant liability
Warrants and Rights Outstanding
Warrant liability
Fair value of warrants
Warrants Not Settleable in Cash, Fair Value Disclosure
Fair value of the warrant issued to the lender
Warrant liability
Weighted average basic and diluted common shares outstanding (in shares)
Weighted Average Number of Shares Outstanding, Basic and Diluted
Unamortized issuance costs
Write off of Deferred Debt Issuance Cost
Redeemable Convertible Preferred Stock
Redeemable Convertible Preferred Stock [Member]
October 2012 Financing
Issuance of Debt [Member]
October 2012 Debt Financing Warrants [Member]
Represents warrants issued in debt financing transactions in October 2012 which expire in 2017.
October 2012 Debt Financing Warrants
Term Loan 2012 Warrants [Member]
2012 Term Loan Warrants
Represents warrants issued to the lender in connection with the 2012 Term Loan which expire in 2017.
Common stock warrants expiring in 2017
May 2010 Term Loan Lenders Warrants [Member]
Represents warrants issued to the lenders in connection with the Term A and Term B loans issues under the May 2010 Term Loan Facility.
Term A and Term B Loan Lender Warrants
Units [Member]
Units
Represents units sold in a financing transaction that consisted of 1/1000 of a share of Series A Preferred Stock and a warrant to purchase one share of common stock.
October 2012 Financing Warrants [Member]
October 2012 Equity Financing Warrants
Represents warrants included in the Units sold in a financing transaction in October 2012 which expire in 2017.
Number of Preferred Series A Shares in Each Unit
Number of shares of preferred stock included in each unit
Number of shares of Series A Preferred Stock included in each unit.
Class of Warrant or Right Number of Securities Called by Each Warrant or Right
Number of securities into which each warrant or right may be converted. For example, but not limited to, each warrant may be converted into two shares.
Number of shares of common stock that can be purchased with each warrant
Dividend rate, description of terms
Preferred Stock, Dividend Payment Rate, Variable
Dividend dollar value on Series A preferred stock per share, calculated as 8% of $2.00 per 1/1000 of a share (in dollars per share)
Preferred Stock, Dividend Rate, Per-Dollar-Amount
Liquidation preference, calculated as $2.00 per 1/1000 share (in dollars per share)
Preferred Stock, Liquidation Preference Per Share
October 2012 Debt and Equity Financing Warrants [Member]
October 2012 Debt and Equity Financing Warrants
Represents warrants issued in debt and equity financing transactions in October 2012 which expire in 2017.
Stock Issuance [Line Items]
Common Stock Purchase Agreement with Aspire Capital
Shares of common stock issued to Aspire Capital as a commitment fee
Stock Issued During Period, Shares, Issued for Services
Initial Public Offering
IPO [Member]
Class of Warrant or Right [Axis]
Financing [Axis]
Issuance of Equity [Member]
Issuance of Equity
Class of Warrant or Right [Domain]
Financing [Domain]
Stock Issued During Period, Gross Value
Represents the value of stock issued during the period, including the value which was allocated to a warrant liability, if any, before transaction costs.
Aggregate purchase price of equity sold
Debt Instrument, Unamortized Discount
Unamortized debt discount
Debt Issuance Cost
Debt issuance costs
Computer Equipment Software Office Equipment and Furniture [Member]
Computer equipment, software, office equipment and furniture
Represents the long-lived, depreciable assets such as computers and that are used in the creation, maintenance and utilization of information systems and purchased software applications and tangible personal property used in an office setting. Along with equipment commonly used in offices and stores that have no permanent connection to the structure of a building or utilities. Examples include, but are not limited to, desks, chairs, tables and bookcases.
Schedule of Maturities of Long-term Debt [Table Text Block]
Schedule of future payments under debt agreements
Maturities of Long-term Debt [Abstract]
Debt Maturities:
Long-term Debt, Fiscal Year Maturity [Abstract]
Principal obligations
Long-term Debt, Maturities, Repayments of Principal in Next Twelve Months
2013
Long-term Debt, Maturities, Repayments of Principal in Year Two
2014
Long-term Debt, Maturities, Repayments of Principal in Year Three
2015
Long-term Debt, Maturities, Repayments of Principal in Year Four
2016
Long Term Debt Maturities Repayments of Principal in Year Five and Thereafter
2017 and thereafter
Amount of long-term debt, sinking fund requirements, and other securities redeemable at fixed or determinable prices and dates maturing in the fifth year and year after the fifth fiscal year following the latest fiscal year.
Interest Payment on Long Term Debt by Maturity [Abstract]
Interest payments on debt
Interest Payment on Long Term Debt
Total
Represents the interest payment on long-term debt, net of unamortized discount or premium, including current and noncurrent amounts. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.
Long Term Debt Maturities Payments of Interest in Next Twelve Months
2013
Amount of interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the next fiscal year following the latest fiscal year.
Long Term Debt Maturities, Payments of Interest in Year Two
2014
Amount of interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the second fiscal year following the latest fiscal year.
Long Term Debt Maturities, Payments of Interest in Year Three
2015
Amount of interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the third fiscal year following the latest fiscal year.
Long Term Debt Maturities, Payments of Interest in Year Four
2016
Amount of interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the fourth fiscal year following the latest fiscal year.
Long Term Debt Maturities, Payments of Interest in Year Five and Thereafter
2017 and thereafter
Amount of interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the fifth year and year after the fifth fiscal year following the latest fiscal year.
Principal and Interest Payment on Long Term Debt by Maturity [Abstract]
Principal and Interest payments on debt
Principal and Interest Payment on Long Term Debt
Total
Represents the principal and interest payment on long-term debt, net of unamortized discount or premium, including current and noncurrent amounts. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.
Long Term Debt Maturities, Payments of Principal and Interest InNextTwelveMonths
2013
Amount of principal and interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the next fiscal year following the latest fiscal year.
Long Term Debt Maturities, Payments of Principal and Interest in Year Two
2014
Amount of principal and interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the second fiscal year following the latest fiscal year.
Long Term Debt Maturities, Payments of Principal and Interest in Year Three
2015
Amount of principal and interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the third fiscal year following the latest fiscal year.
Long Term Debt Maturities, Payments of Principal and Interest in Year Four
2016
Amount of principal and interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the fourth fiscal year following the latest fiscal year.
Long Term Debt Maturities, Payments of Principal and Interest in Year Five and Thereafter
2017 and thereafter
Amount of principal and interest payment on long-term debt, sinking fund requirements and other securities redeemable at fixed or determinable prices and dates maturing in the fifth year and year after the fifth fiscal year following the latest fiscal year.
Share Based Compensation Arrangement by Share Based Payment Award, Number of Additional Shares Authorized in Percentage
Number of additional shares that will become available for issuance (as a percent)
Represents the percentage of common stock, which is used to issue additional shares authorized for issuance under the established share-based compensation plan.
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Share Based Awards Other than Options Incremental and Associated with Exchange
Unrecognized cost incremental and associated with the exchange
Represents the incremental unrecognized cost associated with the exchange of share-based awards, other than options, made to employees under an equity-based compensation plan, that have yet to vest.
Expected Expenses and Losses Related to Foreign Currency Translation Adjustment
Expected expenses based on exchange rates effect
Represents the expected expenses and losses due to foreign currency translation adjustment.
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Schedule of components of benefit for income taxes attributable to continuing operations
Federal Income Tax Expense (Benefit), Continuing Operations [Abstract]
Federal:
Current Federal Tax Expense (Benefit)
Current
Deferred Federal Income Tax Expense (Benefit)
Deferred
Federal Income Tax Expense (Benefit), Continuing Operations
Total
State and Local Income Tax Expense (Benefit), Continuing Operations [Abstract]
State:
Current State and Local Tax Expense (Benefit)
Current
Deferred State and Local Income Tax Expense (Benefit)
Deferred
State and Local Income Tax Expense (Benefit), Continuing Operations
Total
Exercised
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Total Intrinsic Value