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Stockholders Equity and Stock Options - Summary of Stock Option Activity (Detail) - $ / shares
6 Months Ended 12 Months Ended
Jun. 30, 2022
Dec. 31, 2021
Stockholders' Equity Note [Abstract]    
Number of shares, Outstanding 2,523,305  
Number of shares, Granted 852,450  
Number of shares, Forfeited/Expired (245,385)  
Number of shares, Outstanding 3,130,370 2,523,305
Number of shares, Exercisable as of June 30, 2022 1,201,628  
Number of shares, Vested and expected to vest as of June 30, 2022 3,130,370  
Weighted average exercise price, balance $ 18.88  
Weighted average exercise price, Granted 7.08  
Weighted average exercise price, Forfeited/Expired 61.54  
Weighted average exercise price, balance 12.32 $ 18.88
Weighted average exercise price, Exercisable as of June 30, 2022 14.98  
Weighted average exercise price, Vested and expected to vest as of June 30, 2022 $ 12.32  
Weighted average remaining contractual term, outstanding 8 years 3 months 18 days 7 years 7 months 6 days
Weighted average remaining contractual term, Exercisable as of June 30, 2022 7 years 4 months 24 days  
Weighted average remaining contractual term, Vested and expected to vest as of June 30, 2022 8 years 3 months 18 days