X0306 4 2018-06-06 0 0001374690 ZAFGEN, INC. ZFGN 0001291895 Barrett Peter C/O ZAFGEN, INC., 175 PORTLAND STREET, 4TH FLOOR BOSTON MA 02114 1 0 1 0 Stock Option (Right to Buy) 6.79 2018-06-06 4 A 0 20000 0.00 A 2028-06-06 Common Stock 20000 20000 D These options were issued under the nonemployee director compensation policy and will vest in full upon the earlier of June 6, 2019 or the date of the 2019 annual meeting of stockholders, subject to the director's continued service on the board of directors, provided that, all shares shall become fully vested upon a change in control of the Company. Exhibit 24 - Power of Attorney /s/ Shoaib Ghias, as Attorney-In-Fact 2018-06-07