POWER OF ATTORNEY

      The   undersigned   hereby   constitutes   and  appoints  each  of Patrick
Sexton, Arthur Reinstein, and Laura Zinanni, signing
singly,  the undersigned's true and lawful attorney-in-fact, for the undersigned
and  in  the  undersigned's  name,  to:  (1)  execute  for  and on behalf of the
undersigned,  in the undersigned's capacity as a 10% stockholder, officer and/or
director  of  Cboe  Global  Markets,  Inc.  (the "Company"), Forms 3, 4 and 5 in
accordance  with  Section  16(a)  of the Securities Exchange Act of 1934 and the
rules thereunder, and any other forms or reports the undersigned may be required
to   file  in  connection  with  the  undersigned's  ownership,  acquisition  or
disposition  of  securities  of the Company; (2) do and perform any and all acts
for  and  on  behalf  of  the undersigned which may be necessary or desirable to
complete  and  execute  any  such  Form  3, 4 or 5, or other form or report, and
timely  file  such form or report with the United States Securities and Exchange
Commission  and  any stock exchange or similar authority; and (3) take any other
action  of  any  type  whatsoever in connection with the foregoing which, in the
opinion of such attorney-in-fact, may be of benefit to, in the best interest of,
or  legally required by, the undersigned, it being understood that the documents
executed  by such attorney-in-fact on behalf of the undersigned pursuant to this
Power  of  Attorney  shall  be  in  such  form  and shall contain such terms and
conditions  as  such  attorney-in-fact  may  approve  in such attorney-in-fact's
discretion.  The  undersigned  hereby  grants to each such attorney-in-fact full
power  and  authority  to  do and perform any and every act and thing whatsoever
requisite,  necessary  or proper to be done in the exercise of any of the rights
and  powers  herein  granted,  as  fully  to  all  intents  and  purposes as the
undersigned  might  or  could  do  if  personally  present,  with  full power of
substitution  or  revocation,  hereby  ratifying  and  confirming  all that such
attorney-in-fact,  or  such  attorney-in-fact's substitute or substitutes, shall
lawfully  do  or  cause  to  be done by virtue of this Power of Attorney and the
rights  and  powers  herein  granted.  The  undersigned  acknowledges  that  the
foregoing  attorneys-in-fact,  in serving in such capacity at the request of the
undersigned,  are  not  assuming,  nor  is  the  Company  assuming,  any  of the
undersigned's  responsibilities  to  comply  with  Section  16 of the Securities
Exchange  Act  of  1934.  This  Power of Attorney shall remain in full force and
effect until the undersigned is no longer required to file Forms 3, 4 and 5 with
respect  to  the undersigned's holdings of and transactions in securities of the
Company, unless earlier revoked by the undersigned in a signed writing delivered
to the foregoing attorneys-in-fact.

      IN  WITNESS  WHEREOF,  I,  the  undersigned,  have  executed this Power of
Attorney as of this 27th day of February 2018.


/s/ John F. Deters
---------------------------
Signature

John F. Deters
Printed Name