<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-09-25</periodOfReport>

    <notSubjectToSection16>false</notSubjectToSection16>

    <issuer>
        <issuerCik>0001373671</issuerCik>
        <issuerName>Isilon Systems, Inc.</issuerName>
        <issuerTradingSymbol>ISLN</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001378830</rptOwnerCik>
            <rptOwnerName>Patel Sujal M</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ISILON SYSTEMS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>3101 WESTERN AVENUE</rptOwnerStreet2>
            <rptOwnerCity>SEATTLE</rptOwnerCity>
            <rptOwnerState>WA</rptOwnerState>
            <rptOwnerZipCode>98121</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>Chief Technology Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-09-25</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>false</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>12500</value>
                    <footnoteId id="F2"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>8.2779</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2937664</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-09-26</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>false</equitySwapInvolved>
                <footnoteId id="F3"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>12500</value>
                    <footnoteId id="F4"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>8.1786</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2925164</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The sales reported were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 31, 2007.</footnote>
        <footnote id="F2">The &quot;Amount&quot; and &quot;Price&quot; disclosed in this Column 4 reflect the aggregate amount of securities and the average sales price (ranging from $8.18 to $8.39 per share) in connection with the following dispositions:   200 shares at $8.18; 100 shares at $8.19; 300 shares at $8.20; 1,400 shares at $8.21; 1,200 shares at $8.22; 1,100 shares at $8.23; 900 shares at $8.24; 500 shares at $8.25; 400 shares at $8.26; 400 shares at $8.27; 100 shares at $8.28; 800 shares at $8.29; 900 shares at $8.30; 400 shares at $8.31; 600 shares at $8.32; 500 shares at $8.33; 800 shares at $8.34; 200 shares at $8.35; 300 shares at $8.36; 500 shares at $8.37; 200 shares at $8.38; 700 shares at $8.39.</footnote>
        <footnote id="F3">The sales reported were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 31, 2007.</footnote>
        <footnote id="F4">The &quot;Amount&quot; and &quot;Price&quot; disclosed in this Column 4 reflect the aggregate amount of securities and the average sales price (ranging from $8.00 to $8.37 per share) in connection with the following dispositions:   4 shares at $8.00; 500 shares at $8.01; 1,033 shares at $8.02; 1,100 shares at $8.03; 800 shares at $8.04; 100 shares at $8.05; 600 shares at $8.06; 563 shares at $8.08; 100 shares at $8.10; 100 shares at $8.14; 200 shares at $8.15; 200 shares at $8.17; 100 shares at $8.19; 200 shares at $8.20; 600 shares at $8.21; 500 shares at $8.22; 1,200 shares at $8.23; 100 shares at $8.25; 700 shares at $8.26; 400 shares at $8.27; 300 shares at $8.28; 700 shares at $8.29; 200 shares at $8.30; 100 shares at $8.31; 800 shares at $8.32; 600 shares at $8.33; 200 shares at $8.34; 100 shares at $8.35; 100 shares at $8.36; 300 shares at $8.37.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Keenan Conder, Attorney-in-Fact</signatureName>
        <signatureDate>2007-09-26</signatureDate>
    </ownerSignature>
</ownershipDocument>
