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Operating Leases
12 Months Ended
Dec. 31, 2025
Leases [Abstract]  
Operating Leases Operating Leases
The Company has commitments under operating leases for office, laboratory, and manufacturing space in Malvern, Pennsylvania and other locations. The Company's corporate headquarters, located in Malvern, Pennsylvania, lease has an initial term of approximately seven years and includes options to extend the lease for up to 10 years, which the Company has not elected to account for since it is not reasonably certain that the Company will exercise such option. The Company's current GMP facility, located in Malvern, Pennsylvania, lease has an initial term of seven years and includes an option to extend the lease for up to five years, which the Company has elected to account for since it is reasonably certain that the Company will exercise such option. The Company leases two other general use facilities, within the United States, which have initial terms of two to three years and contain no option to extend.
The components of lease expense were as follows (in thousands):
Year ended December 31,
20252024
Operating lease cost$1,379 $893 
Variable lease cost480 355 
Total lease cost$1,859 $1,248 
Supplemental balance sheet information related to leases was as follows (in thousands):
As of December 31,
20252024
Right-of-use assets, net$4,092 $3,613 
Current lease obligations$858 $519 
Non-current lease obligations3,494 3,313 
Total lease liabilities$4,352 $3,832 
Supplemental information related to leases was as follows:
Year ended December 31,
20252024
Cash paid for amounts included in the measurement of operating lease liabilities included in operating cash flows
$1,168$814
Weighted-average remaining lease terms (years)5.15.9
Weighted-average discount rate10.3 %9.4 %
Future minimum base rent payments are approximately as follows (in thousands):
For the years ending December 31,Amount
2026$1,247 
20271,184 
20281,203 
2029973 
2030384 
Thereafter661 
Total$5,652 
Less: present value adjustment(1,300)
Present value of minimum lease payments$4,352