Income Taxes (Tables)

12 Months Ended

Dec. 31, 2024

Income Tax Disclosure [Abstract]

Schedule of Company's losses before income taxes and provision (benefit) for income taxes

The Company's losses before income taxes and provision (benefit) for income taxes is as follows (in thousands):

	Year ended December 31,
	2024		2023
Loss before income taxes	$	(54,054)	$	(63,078)
Provision (benefit) for income taxes	—		—

Schedule of Effective Income Tax Rate

A reconciliation of the federal statutory income tax rate to the Company's effective income tax rate is as follows:

	Year ended December 31,
	2024		2023
Expected provision at statutory rate	21.0	%	21.0	%
State income tax, net of federal benefit	5.9	%	6.4	%
Tax credits	3.7	%	3.5	%
Change in state tax rate	(2.4)	%	(2.8)	%
Expired Capita Loss	(13.2)	%	—	%
Other, net	(2.0)	%	(1.6)	%
Change in valuation allowance	(13.0)	%	(26.5)	%
Effective tax rate	—	%	—	%

Schedule of Deferred Tax Assets

The Company's deferred tax assets (liabilities) are comprised of the following (in thousands):

	As of December 31,
	2024		2023
Deferred tax assets:
Net operating loss carryforwards	$	67,818	$	58,324
Capital loss carryforwards	—		7,298
Start-up costs	9,699		9,699
Accruals and reserves	672		276
Intellectual property	4,074		4,565
Stock-based compensation	3,063		2,873
Capitalization of research and development expense	20,800		18,702
Deferred revenue	1,784		1,293
Tax credits	11,641		9,324
Lease liabilities	966		977
Total deferred tax assets	120,517		113,331
Valuation allowance	(119,616)		(112,413)
Deferred tax assets, net of valuation allowance	$	901	$	918
Deferred tax liabilities:
Lease right-of-use assets	(901)		(918)
Net deferred tax assets	$	—	$	—

Schedule of Unrecognized Tax Benefits

A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows (in thousands):

	Year ended December 31,
	2024		2023
Gross unrecognized tax benefits at beginning of year	$	303	$	303
Additions for tax positions taken in a prior year	—		—
Additions for tax positions taken in the current year	—		—
Reductions for tax positions taken in the prior year due to settlement	—		—
Reductions for tax positions taken in the prior year due to statutes lapsing	—		—
Gross unrecognized tax benefits at end of year	$	303	$	303