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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Jun. 30, 2023
Jun. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2023
Dec. 31, 2022
Total revenue $ 3,699 $ 485 $ 443 $ 466 $ 643 $ 500 $ 928 $ 1,143 $ 4,627 $ 1,609 $ 6,036 $ 2,488
Operating expenses                        
Research and development 7,048 14,574 10,172 17,937 11,602 9,393 24,746 20,995 31,794 38,932 39,573 56,159
General and administrative 9,082 9,451 8,306 7,639 10,617 10,137 17,757 20,754 26,839 28,393 31,994 35,400
Total operating expenses 16,130 24,025 18,478 25,576 22,219 19,530 42,503 41,749 58,633 67,325 71,567 91,559
Loss from operations (12,431) (23,540) (18,035) (25,110) (21,576) (19,030) (41,575) (40,606) (54,006) (65,716) (65,531) (89,071)
Other income (expense), net 714 475 709 1,197 94 15 1,184 109 1,898 1,306 2,453 2,267
Net loss (11,717) (23,065) (17,326) (23,913) (21,482) (19,015) (40,391) (40,497) (52,108) (64,410) (63,078) (86,804)
Other comprehensive income (loss)                        
Foreign currency translation adjustment 5 (2) (1) 20 10 0 (3) 10 2 30 (5) 25
Unrealized gain (loss) on marketable securities 0 (1)   0 0   (1) 0 (1) 0 (1) 1
Comprehensive loss $ (11,712) $ (23,068) $ (17,327) $ (23,893) $ (21,472) $ (19,015) $ (40,395) $ (40,487) $ (52,107) $ (64,380) $ (63,084) $ (86,778)
Shares used in calculating net loss per common share - basic (in shares) 256,492,558 238,311,498 225,523,627 216,591,011 215,862,977 205,693,498 231,952,888 210,806,330 240,222,667 212,755,746 244,327,057 214,600,051
Shares used in calculating net loss per common share - diluted (in shares) 256,492,558 238,311,498 225,523,627 216,591,011 215,862,977 205,693,498 231,952,888 210,806,330 240,222,667 212,755,746 244,327,057 214,600,051
Net loss per share of common stock - basic (in USD per share) $ (0.05) $ (0.10) $ (0.08) $ (0.11) $ (0.10) $ (0.09) $ (0.17) $ (0.19) $ (0.22) $ (0.30) $ (0.26) $ (0.40)
Net loss per share of common stock - diluted (in USD per share) $ (0.05) $ (0.10) $ (0.08) $ (0.11) $ (0.10) $ (0.09) $ (0.17) $ (0.19) $ (0.22) $ (0.30) $ (0.26) $ (0.40)
Collaborative arrangement revenue                        
Total revenue $ 3,699 $ 485 $ 443 $ 466 $ 643 $ 500 $ 928 $ 1,143 $ 4,627 $ 1,609 $ 6,036 $ 2,488
Operating expenses                        
Research and development                     $ 5,300 $ 9,100