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Stock-Based Compensation (Tables)
 12 Months Ended
Dec. 31, 2022
Share-Based Payment Arrangement [Abstract]  
Schedule of Stock-based Compensation Expense for Options Granted Reflected in the Consolidated Statement of Operations and Comprehensive Loss
Stock-based compensation expense for stock options and RSUs is reflected in the consolidated statements of operations and comprehensive loss as follows (in thousands):
Year ended December 31,
20222021
General and administrative$7,777 $4,909 
Research and development2,764 2,049 
Total$10,541 $6,958 
Schedule of Weighted Average Assumptions Utilized in Fair Value Calculation
The assumptions utilized in the fair value calculations for stock options as of December 31, 2022 and 2021 were as follows:
Year ended December 31,
20222021
Weighted average expected option term (years)5.96.0
Range of expected stock price volatility
106% – 110%
109% – 116%
Weighted average expected stock price volatility107%111%
Range of risk-free interest rate
1.4% – 4.2%
0.4% – 1.4%
Expected dividend rate0%0%
Schedule of Stock Option Activity
The following table summarizes the stock option activity:
Number of SharesWeighted Average Exercise PriceWeighted Average Remaining Contractual Life (Years)Aggregate Intrinsic Value (In Thousands)
Options outstanding at December 31, 202110,086,167 $2.59 8.8$24,664 
Granted6,024,830 3.82 — 
Exercised(1,540,142)0.86 2,592 
Forfeited(3,719,568)4.25 483 
Options outstanding at December 31, 202210,851,287 $2.95 8.3$1,385 
Options exercisable at December 31, 20222,950,927 $2.92 7.6$548 
Schedule of Share-based Payment Arrangement, Restricted Stock Unit, Activity
The following table summarizes the RSU activity:
Number of SharesWeighted Average Grant-Date Fair ValueAggregate Intrinsic Value (In Thousands)
RSUs outstanding at December 31, 2021191,811 $6.79 $873 
Granted1,359,393 4.05 5,509 
Vested(63,123)6.60 157 
Forfeited(563,271)4.59 1,242 
RSUs outstanding at December 31, 2022924,810 $4.12 $1,202