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Stock-based Compensation (Tables)
9 Months Ended
Sep. 30, 2020
Share-based Payment Arrangement [Abstract]  
Schedule of Stock-based Compensation Expense for Options Granted Reflected in the Consolidate Statement of Operations and Comprehensive Loss
Stock-based compensation expense for options granted is reflected in the condensed consolidated statements of operations and comprehensive loss as follows:
Three months ended September 30,Nine months ended September 30,
2020201920202019
General and administrative$100,903 $48,226 $248,942 $298,621 
Research and development25,387 144,779 249,070 421,393 
Total$126,290 $193,005 $498,012 $720,014 
Schedule of Stock Option Activity
The following table summarizes the stock option activity under the Plans:
Number of SharesWeighted Average Exercise PriceWeighted Average Remaining Contractual Life (Years)Aggregate Intrinsic Value
Options outstanding at December 31, 2019
731,189 $4.59 8.0$24,028 
Granted4,064,950 $0.41 
Forfeited(527,862)$1.96 
Options outstanding at September 30, 2020
4,268,277 $0.94 9.1$7,072 
Options exercisable at September 30, 2020
450,405 $4.34 6.6$450