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Stock-Based Compensation - Summary of Weighted-Average Assumptions Used in the Black-Scholes Option Pricing Model to Determine the Fair Value of the Employee Stock Option Grants (Detail)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions And Methodology [Abstract]        
Risk-free interest rate 2.92% 1.95% 2.77% 2.03%
Expected volatility 86.40% 60.00% 87.50% 63.10%
Expected term (in years) 6 years 29 days 6 years 29 days 6 years 29 days 6 years 29 days
Expected dividend yield 0.00% 0.00% 0.00% 0.00%