Collaborative Arrangements - Additional Information (Detail) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Collaborative Arrangements [Line Items]
Period of collaboration agreement			10 years
Upfront License Fee	$ 29,316,658	$ 30,897,444	$ 88,057,894	$ 72,183,782
Expenses In Connection With Collaborative Arrangement	3,749,233	4,597,039	$ 12,321,687	12,534,362
Period of collaboration agreement			10 years
Upfront fee	150,000		$ 150,000
Collaborative Arrangement [Member]
Collaborative Arrangements [Line Items]
Milestone payments			2,000,000.0
Milestone payments income			0	0
Upfront License Fee			0	0
Expenses In Connection With Collaborative Arrangement	0	$ 32,000	$ 4,200	$ 70,000
Collaborative Arrangement [Member] | KYE Pharmaceuticals [Member] | CA [Member]
Collaborative Arrangements [Line Items]
Period of collaboration agreement			10 years
Period of collaboration agreement			10 years
Upfront fee			$ 150,000
Collaborative Arrangement [Member] | KYE Pharmaceuticals [Member] | CA [Member] | Selling, General and Administrative Expenses [Member]
Collaborative Arrangements [Line Items]
Expenses In Connection With Collaborative Arrangement	$ 161,000		$ 161,000