We are not currently a party to any material legal proceedings, and we are not aware of any pending or threatened litigation against us that could have a material adverse effect on our business, operating results or financial condition.

The Company has a non-cancelable sublease agreement for its corporate headquarters in Boston, MA expiring in 2023, and it has a non-cancelable lease agreement for its manufacturing space in Boston and office space in Fort Worth, TX both expiring in 2025 with early termination available at the company’s discretion in 2023. Termination options were not included in the lease term for the Company’s existing operating leases. Certain arrangements have discounted rent periods or escalating rent payment provisions. Leases with an initial term of twelve months or less are not recorded on the consolidated balance sheets. We recognize rent expense on a straight-line basis over the lease term.

As of June 30, 2022, operating lease assets were $695,933. The amount and the maturity of the Company’s operating lease liabilities as of June 30, 2022, are as follows:


	June 30, 2022
2022 (June 30 - December 31)	$	275,625
2023		411,142
2034		159,872
2025		67,981
2026		—
Thereafter		—
Total future minimum lease payments		914,620
Less imputed interest		149,197
Total operating lease liabilities	$	765,423
Included in the condensed consolidated balance sheet:
Current operating lease liabilities	$	436,694
Non-current operating lease liabilities		328,729
Total operating lease liabilities	$	765,423

For the three and six months ended June 30, 2022 and 2021, the total lease cost is comprised of the following amounts:


	For the Three Months Ended June 30,				For the Six Months Ended June 30,
	2022		2021		2022		2021
Operating lease expense		125,293		102,963		241,904		170,472
Short-term lease expense		1,300		2,175		3,250		25,859
Total lease expense	$	126,593	$	105,138	$	245,154	$	196,331

The following summarizes additional information related to operating leases:


	June 30, 2022
Weighted-average remaining lease term (in years)		2.1
Weighted-average discount rate		20	%

For the three and six months ended June 30, 2022 and 2021, there were no customers which accounted for more than 10% of product revenues. For the three and six months ended June 30, 2022 a U.S. insurance payer represented 28% and 31% of product revenues, respectively. For the three and six months ended June 30, 2021 a U.S. insurance payer represented 30% and 28% of product revenues, respectively.

At both June 30, 2022 and 2021, one insurance company and its affiliates accounted for approximately 68% of accounts receivable, respectively.

For the three and six months ended June 30, 2022 , approximately 71% and 63% of the Company's product revenues, respectively, were derived from patients with Medicare Advantage insurance plans. For the three and six months ended June 30, 2021, approximately 52% and 54% of the Company’s product revenues were derived from patients with Medicare Advantage insurance plans, respectively.