Income Taxes (Tables)

12 Months Ended

Dec. 31, 2012

Income Tax Disclosure [Abstract]

Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]

	Year Ended December 31,
	2012			2011
Current:
Federal	$	—		$	—
State		5,726			—
Foreign		(27,179	)		27,247
Total Current	$	(21,453	)	$	27,247
Deferred:
Federal	$	—		$	—
State		—			—
Foreign		—			—
Total Deferred	$	—		$	—
Provision for income taxes	$	(21,453	)	$	27,247

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

	Year Ended December 31,
	2012			2011
Provision for income taxes at federal statutory rate	$	(2,787,359	)	$	(4,460,063	)
Federal research and development tax credits		(94,794	)		(160,003	)
Expenses not deductible, income not taxable		(473,203	)		(2,705,607	)
Foreign loss taxed at lower rates		164,828			232,280
Change in federal valuation allowance		3,169,075			7,120,640
Provision for income taxes	$	(21,453	)	$	27,247

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

	December 31,		December 31,
	2012		2011
Deferred tax assets:
Net operating loss carry-forwards	$	25,034,778	$	21,588,554
Capitalized start-up cost and research and development cost		607,983		891,708
Research and development tax credit		1,389,625		1,239,795
Depreciation on property and equipment		(156,361)		(366,292)
Stock-based compensation		405,742		677,381
Reserves and accruals		719,909		666,336
Total deferred tax asset		28,001,676		24,697,482
Valuation allowance		(28,001,676)		(24,697,482)
Net deferred tax assets	$	—	$	—

Schedule Of Deferred Income Tax [Table Text Block]

	Year Ended December 31,
	2012			2011
Deferred tax assets:
Net operating loss carry-forwards	$	3,446,224		$	6,635,471
Capitalized start-up cost and research and development cost		(283,725	)		127,807
Research and development tax credit		149,830			(274,775	)
Depreciation on property and equipment		209,931			(476,501	)
Stock-based compensation		(271,639	)		677,381
Reserves and accruals		53,573			519,602
Valuation allowance		(3,304,194	)		(7,208,985	)
Net deferred income taxes	$	—		$	—

Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]

	Year Ended December31,
		2012		2011
Beginning Balance	$	645,000	$	—
Additions based on tax positions related to prior years		—		497,000
Additions based on tax positions related to the current year		76,000		148,000
Ending Balance	$	721,000	$	645,000