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4. DEBT (Tables) - Oxford Loan
 6 Months Ended
Jun. 30, 2018
Summary of notes payable
   June 30, 2018  December 31, 2017
       
Notes payable:  $30,000,000   $30,000,000 
Less:          
Debt discount   (4,121,919)   (4,631,542)
Senior notes payable  $25,878,081   $25,368,458 
Summary of related party notes payable
   June 30, 2018  December 31, 2017
Biotest - Gross proceeds  $15,000,000   $15,000,000 
Less:          
Debt discount   (142,092)   (157,304)
Note payable - related party  $14,857,908   $14,842,696