INCOME TAXES, Reconciliation of Income Taxes (Details) - USD ($)	12 Months Ended
Dec. 31, 2022	Dec. 31, 2021
INCOME TAXES [Abstract]
Benefit at U.S. Federal statutory rate	$ (13,839,830)	$ (15,045,999)
State taxes - deferred	(1,773,349)	(251,839)
Increase in valuation allowance	15,117,100	14,618,762
Research and development credits	(211,343)	(239,585)
Decrease in federal net operating loss	0	623,679
162(m) disallowance	862,027	63,515
Other	(154,605)	231,467
Benefit for income taxes	$ 0	$ 0

Amount of increase (decrease) of federal net operating loss in the valuation allowance for deferred tax assets.

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Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to section 162(m) disallowance.

+ References

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Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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The amount of income tax expense or benefit for the period computed by applying the domestic federal statutory tax rates to pretax income from continuing operations.

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