STOCKHOLDERS' EQUITY, Equity Incentive Plans (Details) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Jan. 03, 2022
Stock Options [Abstract]
Shares reserved for grant (in shares)	29,177,763
Number of stock options granted (in shares)	1,194,032	1,895,550
Weighted average remaining contractual life of stock options, outstanding	6 years 1 month 6 days
Weighted average remaining contractual life of stock options, expected to vest	6 years 1 month 6 days
Weighted average remaining contractual life of stock options, exercisable	5 years 3 months 18 days
Stock Option Outstanding and Exercisable [Abstract]
Outstanding at beginning of period (in shares)	8,256,211
Weighted average remaining contractual life of stock options, outstanding	6 years 1 month 6 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 3.37
Options outstanding, aggregate intrinsic value	$ 7,640,242
Options exercisable (in shares)	6,213,959
Weighted average remaining contractual life of stock options, exercisable	5 years 3 months 18 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 3.8
Options exercisable, aggregate intrinsic value	$ 3,886,055
Restricted Stock Units [Abstract]
Restricted stock units vested over a period	4 years
Total stock-based compensation expense, Amount [Abstract]
Stock-based compensation	$ 5,214,531	$ 3,488,253
Research and Development [Member]
Total stock-based compensation expense, Amount [Abstract]
Stock-based compensation	19,476	153,924
Plasma Center Operating Expenses [Member]
Total stock-based compensation expense, Amount [Abstract]
Stock-based compensation	81,668	60,257
Selling, General and Administrative [Member]
Total stock-based compensation expense, Amount [Abstract]
Stock-based compensation	4,716,219	2,958,008
Cost of Product Revenue [Member]
Total stock-based compensation expense, Amount [Abstract]
Stock-based compensation	$ 397,168	$ 316,064
$1.10 - $1.67 [Member]
Stock Options [Abstract]
Weighted average remaining contractual life of stock options, outstanding	9 years 1 month 6 days
Stock Option Outstanding and Exercisable [Abstract]
Exercise price range, lower limit (in dollars per share)	$ 1.1
Exercise price range, upper limit (in dollars per share)	$ 1.67
Outstanding at beginning of period (in shares)	1,523,824
Weighted average remaining contractual life of stock options, outstanding	9 years 1 month 6 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 1.61
Options outstanding, aggregate intrinsic value	$ 3,452,237
Options exercisable (in shares)	406,160
Weighted average remaining contractual life of stock options, exercisable	9 years
Options exercisable, weighted average exercise price (in dollars per share)	$ 1.52
Options exercisable, aggregate intrinsic value	$ 959,663
$1.73 - $2.60 [Member]
Stock Options [Abstract]
Weighted average remaining contractual life of stock options, outstanding	8 years
Stock Option Outstanding and Exercisable [Abstract]
Exercise price range, lower limit (in dollars per share)	$ 1.73
Exercise price range, upper limit (in dollars per share)	$ 2.6
Outstanding at beginning of period (in shares)	1,623,353
Weighted average remaining contractual life of stock options, outstanding	8 years
Options outstanding, weighted average exercise price (in dollars per share)	$ 2.35
Options outstanding, aggregate intrinsic value	$ 2,491,181
Options exercisable (in shares)	943,200
Weighted average remaining contractual life of stock options, exercisable	8 years
Options exercisable, weighted average exercise price (in dollars per share)	$ 2.36
Options exercisable, aggregate intrinsic value	$ 1,430,931
$2.62 - $3.93 [Member]
Stock Options [Abstract]
Weighted average remaining contractual life of stock options, outstanding	5 years
Stock Option Outstanding and Exercisable [Abstract]
Exercise price range, lower limit (in dollars per share)	$ 2.62
Exercise price range, upper limit (in dollars per share)	$ 3.93
Outstanding at beginning of period (in shares)	4,083,311
Weighted average remaining contractual life of stock options, outstanding	5 years
Options outstanding, weighted average exercise price (in dollars per share)	$ 3.46
Options outstanding, aggregate intrinsic value	$ 1,696,824
Options exercisable (in shares)	3,852,447
Weighted average remaining contractual life of stock options, exercisable	4 years 9 months 18 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 3.49
Options exercisable, aggregate intrinsic value	$ 1,495,461
$3.98 - $5.97 [Member]
Stock Options [Abstract]
Weighted average remaining contractual life of stock options, outstanding	4 years 8 months 12 days
Stock Option Outstanding and Exercisable [Abstract]
Exercise price range, lower limit (in dollars per share)	$ 3.98
Exercise price range, upper limit (in dollars per share)	$ 5.97
Outstanding at beginning of period (in shares)	470,428
Weighted average remaining contractual life of stock options, outstanding	4 years 8 months 12 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 5.03
Options outstanding, aggregate intrinsic value	$ 0
Options exercisable (in shares)	456,857
Weighted average remaining contractual life of stock options, exercisable	4 years 7 months 6 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 5.06
Options exercisable, aggregate intrinsic value	$ 0
$6.02 - $9.03 [Member]
Stock Options [Abstract]
Weighted average remaining contractual life of stock options, outstanding	1 year 6 months
Stock Option Outstanding and Exercisable [Abstract]
Exercise price range, lower limit (in dollars per share)	$ 6.02
Exercise price range, upper limit (in dollars per share)	$ 9.03
Outstanding at beginning of period (in shares)	307,795
Weighted average remaining contractual life of stock options, outstanding	1 year 6 months
Options outstanding, weighted average exercise price (in dollars per share)	$ 8.05
Options outstanding, aggregate intrinsic value	$ 0
Options exercisable (in shares)	307,795
Weighted average remaining contractual life of stock options, exercisable	1 year 6 months
Options exercisable, weighted average exercise price (in dollars per share)	$ 8.05
Options exercisable, aggregate intrinsic value	$ 0
$9.37 - $10.80 [Member]
Stock Options [Abstract]
Weighted average remaining contractual life of stock options, outstanding	1 year 10 months 24 days
Stock Option Outstanding and Exercisable [Abstract]
Exercise price range, lower limit (in dollars per share)	$ 9.37
Exercise price range, upper limit (in dollars per share)	$ 10.8
Outstanding at beginning of period (in shares)	247,500
Weighted average remaining contractual life of stock options, outstanding	1 year 10 months 24 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 10.28
Options outstanding, aggregate intrinsic value	$ 0
Options exercisable (in shares)	247,500
Weighted average remaining contractual life of stock options, exercisable	1 year 10 months 24 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 10.28
Options exercisable, aggregate intrinsic value	$ 0
2014 Omnibus Incentive Compensation Plan [Member]
Stock Options [Abstract]
Shares reserved for grant (in shares)	2,334,940
Shares available for issuance (in shares)		69,090
Equity Incentive Plans [Member]
Stock Options [Abstract]
Percentage of outstanding shares of common stock	4.00%
Shares available for issuance (in shares)	10,000,000		7,901,643
Stock Option Outstanding and Exercisable [Abstract]
Unrecognized compensation expense, stock options	$ 2,300,000
Unrecognized compensation expense recognition period	2 years 2 months 12 days
Stock Options [Member]
Fair Value Assumptions and Methodology [Abstract]
Dividend yield	0.00%	0.00%
Stock Option, Shares [Abstract]
Options outstanding, vested and expected to vest, beginning balance (in shares)	7,862,722	6,922,931
Forfeited (in shares)	(31,540)	(529,202)
Expired (in shares)	(700,324)	(426,557)
Granted (in shares)	1,194,032	1,895,550
Exercised (in shares)	(68,679)	0
Options outstanding, vested and expected to vest, ending balance (in shares)	8,256,211	7,862,722
Options exercisable (in shares)	6,213,959
Stock Options, Weighted Average Exercise Price [Abstract]
Options outstanding, vested and expected to vest, weighted average exercise price, beginning balance (in dollars per share)	$ 3.93	$ 4.4
Forfeited, weighted average exercise price (in dollars per share)	2.37	2.89
Expired, weighted average exercise price (in dollars per share)	6.86	4.91
Granted, weighted average exercise price (in dollars per share)	1.67	2.14
Exercised, weighted average exercise price (in dollars per share)	2.55	0
Options outstanding, vested and expected to vest, weighted average exercise price, ending balance (in dollars per share)	3.37	$ 3.93
Options exercisable, weighted average exercise price (in dollars per share)	$ 3.8
Stock Options [Member] | Minimum [Member]
Fair Value Assumptions and Methodology [Abstract]
Expected term	5 years 6 months	5 years 6 months
Volatility		68.00%
Risk-free interest rate	1.72%	0.80%
Stock Options [Member] | Maximum [Member]
Fair Value Assumptions and Methodology [Abstract]
Expected term	6 years 3 months 18 days	6 years 3 months 18 days
Volatility	68.00%	70.00%
Risk-free interest rate	1.73%	1.27%
Restricted Stock Units (RSUs) [Member]
Stock Option Outstanding and Exercisable [Abstract]
Unrecognized compensation expense, non option		$ 3,800,000
Unrecognized compensation expense recognition period		2 years 4 months 24 days
Restricted Stock Units [Abstract]
Number of restricted stock units granted (in shares)	1,174,266	4,384,744
Shares withheld for tax withholding obligation (in shares)	918,851	27,850
Amount of shares withheld for tax withholding obligation	$ 2,900,000	$ 62,000,000
Unvested RSU, Shares [Abstract]
Beginning balance (in shares)	4,485,133	326,000
Granted (in shares)	1,174,266	4,384,744
Vested (in shares)	(2,727,412)	(92,750)
Forfeited (in shares)	(65,000)	(132,861)
Ending balance (in shares)	2,866,987	4,485,133
Unvested RSU, Weighted Average Grant Date Fair Value
Unvested, Weighted average grant date fair value, beginning balance (in dollars per share)	$ 1.34	$ 2.81
Granted, Weighted average grant date fair value (in dollars per share)	1.74	1.3
Vested, Weighted average grant date fair value (in dollars per share)	1.25	2.82
Forfeited, Weighted average grant date fair value (in dollars per share)	1.4	2.51
Unvested, Weighted average grant date fair value, ending balance (in dollars per share)	$ 1.59	$ 1.34
Restricted Stock Units (RSUs) [Member] | Employees [Member]
Restricted Stock Units [Abstract]
Restricted stock units vested over a period	4 years
Restricted Stock Units (RSUs) [Member] | Directors [Member]
Restricted Stock Units [Abstract]
Restricted stock units vested over a period	1 year
Restricted Stock Units (RSUs) [Member] | Employee Retention Program [Member]
Restricted Stock Units [Abstract]
Number of restricted stock units granted (in shares)		3,832,500
Time Based Restricted Stock (RSUs) [Member] | Employee Retention Program [Member]
Restricted Stock Units [Abstract]
Number of restricted stock units granted (in shares)		2,685,000
Time Based Restricted Stock (RSUs) [Member] | Employee Retention Program [Member] | Tranche One [Member]
Restricted Stock Units [Abstract]
Vesting percentage of RSUs granted under retention bonus program	50.00%
Milestone Based Restricted Stock (RSUs) [Member] | Employee Retention Program [Member]
Restricted Stock Units [Abstract]
Number of restricted stock units granted (in shares)		1,147,500