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STOCKHOLDERS' EQUITY, Equity Incentive Plans (Details) - USD ($)
3 Months Ended
Mar. 23, 2022
Mar. 31, 2022
Mar. 31, 2021
Restricted Stock Units [Abstract]      
Restricted stock units vested over a period   4 years  
Total stock-based compensation expense, Amount [Abstract]      
Total stock-based compensation expense   $ 1,641,388 $ 781,397
Hayfin Credit Agreement [Member]      
Fair Value Assumptions and Methodology [Abstract]      
Expected term   7 years  
Volatility 68.10%    
Dividend yield 0.00%    
Risk-free interest rate 2.36%    
Research and Development [Member]      
Total stock-based compensation expense, Amount [Abstract]      
Total stock-based compensation expense   $ 4,671 105,227
Plasma Center Operating Expenses [Member]      
Total stock-based compensation expense, Amount [Abstract]      
Total stock-based compensation expense   21,052 10,818
Selling, General and Administrative [Member]      
Total stock-based compensation expense, Amount [Abstract]      
Total stock-based compensation expense   1,517,602 588,491
Cost of Product Revenue [Member]      
Total stock-based compensation expense, Amount [Abstract]      
Total stock-based compensation expense   98,063 $ 76,861
Equity Incentive Plans [Member]      
Stock Options, Weighted Average Exercise Price [Abstract]      
Unrecognized compensation expense, stock options   $ 3,800,000  
Unrecognized compensation expense recognition period   2 years 7 months 6 days  
Stock Options [Member]      
Fair Value Assumptions and Methodology [Abstract]      
Volatility   68.00% 69.00%
Dividend yield   0.00% 0.00%
Stock Options [Abstract]      
Number of stock options granted (in shares)   1,194,032 1,441,050
Weighted average remaining contractual life of stock options, outstanding   6 years 7 months 6 days  
Weighted average remaining contractual life of stock options, expected to vest   6 years 7 months 6 days  
Weighted average remaining contractual life of stock options, exercisable   5 years 3 months 18 days  
Stock Option, Shares [Abstract]      
Options outstanding, vested and expected to vest, beginning balance (in shares)   7,862,722  
Forfeited (in shares)   (9,186)  
Expired (in shares)   (361,500)  
Granted (in shares)   1,194,032  
Options outstanding, vested and expected to vest, ending balance (in shares)   8,686,068  
Options exercisable (in shares)   5,646,819  
Stock Options, Weighted Average Exercise Price [Abstract]      
Options outstanding, vested and expected to vest, weighted average exercise price, beginning balance (in dollars per share)   $ 3.93  
Forfeited, weighted average exercise price (in dollars per share)   2.13  
Expired, weighted average exercise price (in dollars per share)   6.48  
Granted, weighted average exercise price (in dollars per share)   1.67  
Options outstanding, vested and expected to vest, weighted average exercise price, ending balance (in dollars per share)   3.51  
Options exercisable, weighted average exercise price (in dollars per share)   $ 4.25  
Stock Options [Member] | Minimum [Member]      
Fair Value Assumptions and Methodology [Abstract]      
Expected term   5 years 6 months 5 years 6 months
Risk-free interest rate   1.72% 0.80%
Stock Options [Member] | Maximum [Member]      
Fair Value Assumptions and Methodology [Abstract]      
Expected term   6 years 3 months 18 days 6 years 3 months 18 days
Risk-free interest rate   1.73% 1.04%
Restricted Stock Units (RSUs) [Member]      
Restricted Stock Units [Abstract]      
Number of restricted stock units granted (in shares)   1,059,266 492,744
Shares withheld for tax withholding obligation (in shares)   265,929  
Amount of shares withheld for tax withholding obligation   $ 400,000  
Unvested RSU, Shares [Abstract]      
Beginning balance (in shares)   4,485,133  
Granted (in shares)   1,059,266  
Vested (in shares)   (799,641)  
Forfeited (in shares)   (15,000)  
Ending balance (in shares)   4,729,758  
Unvested RSU, Weighted Average Grant Date Fair Value      
Unvested, Weighted average grant date fair value, beginning balance (in dollars per share)   $ 1.34  
Granted, Weighted average grant date fair value (in dollars per share)   1.67  
Vested, Weighted average grant date fair value (in dollars per share)   1.41  
Forfeited, Weighted average grant date fair value (in dollars per share)   1.22  
Unvested, Weighted average grant date fair value, ending balance (in dollars per share)   $ 1.41  
Restricted Stock Units (RSUs) [Member] | Directors [Member]      
Restricted Stock Units [Abstract]      
Restricted stock units vested over a period   1 year  
Restricted Stock Units (RSUs) [Member] | Employees [Member]      
Restricted Stock Units [Abstract]      
Restricted stock units vested over a period   4 years  
Restricted Stock Units (RSUs) [Member] | Equity Incentive Plans [Member]      
Stock Options, Weighted Average Exercise Price [Abstract]      
Unrecognized compensation expense recognition period   2 years 8 months 12 days  
Unvested RSU, Weighted Average Grant Date Fair Value      
Unrecognized compensation expense, non option   $ 5,700,000  
Milestone Based Restricted Stock (RSUs) [Member] | BIVIGAM [Member]      
Unvested RSU, Shares [Abstract]      
Vested (in shares)   (382,117)  
Milestone Based Restricted Stock (RSUs) [Member] | Hayfin Credit Agreement [Member]      
Unvested RSU, Shares [Abstract]      
Vested (in shares)   (254,745)