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Income Taxes - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Income Taxes [Line Items]      
Income tax paid $ 0 $ 0 $ 0
U.S. Federal      
Income Taxes [Line Items]      
Net operating loss carryforwards 151,400,000    
Research and development tax credit 10,000,000    
Foreign      
Income Taxes [Line Items]      
Net operating loss carryforwards 21,600,000    
State and City      
Income Taxes [Line Items]      
Net operating loss carryforwards 65,500,000    
Subject To Annual Limitations | U.S. Federal      
Income Taxes [Line Items]      
Net operating loss carryforwards 16,800,000    
Not Subject To Annual Limitations | U.S. Federal      
Income Taxes [Line Items]      
Net operating loss carryforwards 116,800,000    
Research and development tax credit 10,000,000    
Not Subject To Annual Limitations | State and City      
Income Taxes [Line Items]      
Net operating loss carryforwards $ 65,300,000