Income Taxes - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Taxes [Line Items]
Income tax paid	$ 0	$ 0	$ 0
U.S. Federal
Income Taxes [Line Items]
Net operating loss carryforwards	326,300,000
Research and development tax credit	20,600,000
U.S. Federal | Subject To Annual Limitations
Income Taxes [Line Items]
Net operating loss carryforwards	189,700,000
U.S. Federal | Not Subject To Annual Limitations
Income Taxes [Line Items]
Net operating loss carryforwards	289,600,000
Research and development tax credit	20,600,000
Foreign
Income Taxes [Line Items]
Net operating loss carryforwards	31,700,000
State and City
Income Taxes [Line Items]
Net operating loss carryforwards	118,700,000
State and City | Not Subject To Annual Limitations
Income Taxes [Line Items]
Net operating loss carryforwards	$ 118,500,000