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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Preferred Stock
Common Stock
Additional Paid-in Capital
Accumulated Deficit
Consolidated entity, excluding related party
Consolidated entity, excluding related party
Common Stock
Consolidated entity, excluding related party
Additional Paid-in Capital
Healios
Healios
Common Stock
Healios
Additional Paid-in Capital
Preferred stock shares, beginning balance (in shares) at Dec. 31, 2016   0                  
Common stock, beginning balance (in shares) at Dec. 31, 2016     86,629,302                
Beginning balance at Dec. 31, 2016 $ 11,181 $ 0 $ 87 $ 329,373 $ (318,279)            
Stock-based compensation 3,154     3,154              
Issuance of common stock from warrant exercises (in shares)     1,843,363                
Issuance of common stock from warrant exercises 1,862   $ 2 1,860              
Issuance of common stock, net of issuance costs (in shares)             33,172,300        
Issuance of common stock, net of issuance costs           $ 39,813 $ 33 $ 39,780      
Issuance of common stock under equity compensation plans (in shares)     432,488                
Issuance of common stock under equity compensation plans (283)     (283)              
Net and comprehensive loss (32,241)       (32,241)            
Preferred stock shares, ending balance (in shares) at Dec. 31, 2017   0                  
Common stock, ending balance (in shares) at Dec. 31, 2017     122,077,453                
Ending balance at Dec. 31, 2017 23,376 $ 0 $ 122 373,884 (350,630)            
Stock-based compensation 3,849     3,849              
Issuance of warrant to Healios at fair value                 $ 1,080   $ 1,080
Issuance of common stock, net of issuance costs (in shares)             9,658,582     12,000,000  
Issuance of common stock, net of issuance costs           16,628 $ 9 16,619 $ 20,995 $ 12 $ 20,983
Issuance of common stock under equity compensation plans (in shares)     556,704                
Issuance of common stock under equity compensation plans (400)   $ 1 (401)              
Net and comprehensive loss $ (24,283)       (24,283)            
Preferred stock shares, ending balance (in shares) at Dec. 31, 2018 0 0                  
Common stock, ending balance (in shares) at Dec. 31, 2018 144,292,739   144,292,739                
Ending balance at Dec. 31, 2018 $ 43,116 $ 0 $ 144 416,014 (373,042)            
Stock-based compensation 4,851     4,851              
Issuance of common stock, net of issuance costs (in shares)             14,825,000        
Issuance of common stock, net of issuance costs           $ 20,284 $ 15 $ 20,269      
Issuance of common stock under equity compensation plans (in shares)     673,846                
Issuance of common stock under equity compensation plans (398)   $ 1 (399)              
Net and comprehensive loss $ (44,582)       (44,582)            
Preferred stock shares, ending balance (in shares) at Dec. 31, 2019 0 0                  
Common stock, ending balance (in shares) at Dec. 31, 2019 159,791,585   159,791,585                
Ending balance at Dec. 31, 2019 $ 23,271 $ 0 $ 160 $ 440,735 $ (417,624)