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Accounting Policies - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Mar. 31, 2019
Jan. 01, 2018
Jan. 01, 2017
Significant Accounting Policies [Line Items]              
Revenue recognized related to the advance from Healios $ 0            
Cumulative effect of accounting change           $ 1,871,000 $ (110,000)
Accrued capital expenditures   $ 100,000          
Payments for royalties 0 0 $ 0        
Sublicense fees 100,000 600,000          
Gain from insurance proceeds, net 0 617,000 0 $ 700,000      
Warrant liabilities $ 0 0          
Contractual term 10 years            
Liability for uncertain income tax $ 0 0          
Dilutive effects from warrant liabilities $ 0 0 $ 0        
Healios              
Significant Accounting Policies [Line Items]              
Unbilled accounts receivable from Healios   3,600,000          
Deposit from Healios   $ 2,000,000          
Minimum              
Significant Accounting Policies [Line Items]              
Estimated useful life of long-lived assets 3 years            
Annual stock-based awards vesting period   3 years          
Maximum              
Significant Accounting Policies [Line Items]              
Estimated useful life of long-lived assets 10 years            
Annual stock-based awards vesting period 4 years            
License | Healios              
Significant Accounting Policies [Line Items]              
Unbilled accounts receivable from Healios         $ 2,500,000    
Retained Earnings              
Significant Accounting Policies [Line Items]              
Cumulative effect of accounting change           1,871,000 $ (110,000)
Retained Earnings | ASU 2014-09              
Significant Accounting Policies [Line Items]              
Cumulative effect of accounting change           $ 1,900,000