X0306 4 2021-06-10 0 0001367920 CONCERT PHARMACEUTICALS, INC. CNCE 0001190474 JAEGER WILFRED E C/O CONCERT PHARMACEUTICALS, INC. 65 HAYDEN AVENUE, SUITE 3000N LEXINGTON MA 02421 1 0 0 0 Common Stock 2021-06-10 4 A 0 5125 A 5125 D Stock Option (right to buy) 4.26 2021-06-10 4 A 0 10250 0.00 A 2031-06-09 Common Stock 10250 10250 D Represents a grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. These RSUs vest in full on the earlier of (i) June 10, 2022 and (ii) the date that is one business day prior to the date of the Issuer's next annual meeting of stockholders. The amount listed represents the maximum number of shares of Common Stock of the Issuer that may be delivered pursuant to the grant. Not applicable. The shares underlying this option vest in equal quarterly installments over a one-year period through June 10, 2022, provided that such option shall vest in full on the date that is one business day prior to the date of the Issuer's next annual meeting of stockholders (if earlier than June 10, 2022). /s/ Jeffrey A. Munsie, attorney-in-fact 2021-06-11