X0306 4 2021-06-10 0 0001367920 CONCERT PHARMACEUTICALS, INC. CNCE 0001185039 ALDRICH RICHARD C/O CONCERT PHARMACEUTICALS, INC. 65 HAYDEN AVENUE, SUITE 3000N LEXINGTON MA 02421 1 0 0 0 Common Stock 2021-06-10 4 A 0 5125 A 342100 D Common Stock 44351 I By Little Eagles, LLC Stock Option (right to buy) 4.26 2021-06-10 4 A 0 10250 0.00 A 2031-06-09 Common Stock 10250 10250 D Stock Option (right to buy) 4.26 2021-06-10 4 A 0 30182 0.00 A 2031-06-09 Common Stock 30182 30182 D Represents a grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. These RSUs vest in full on the earlier of (i) June 10, 2022 and (ii) the date that is one business day prior to the date of the Issuer's next annual meeting of stockholders. The amount listed represents the maximum number of shares of Common Stock of the Issuer that may be delivered pursuant to the grant. Not applicable. Shares held by Little Eagles, LLC. The owners of Little Eagles, LLC are the Richard H. Aldrich Irrevocable Trust of 2011 and trusts established for the benefit of Mr. Aldrich's minor children. The trustees of the Richard H. Aldrich Irrevocable Trust of 2011 are Mr. Aldrich's spouse, Nichole A. Aldrich, and Mr. Aldrich's brother, Caleb F. Aldrich. The beneficiaries of the Richard H. Aldrich Irrevocable Trust of 2011 are Mr. Aldrich's minor children. Mr. Aldrich disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. The shares underlying this option vest in equal quarterly installments over a one-year period through June 10, 2022, provided that such option shall vest in full on the date that is one business day prior to the date of the Issuer's next annual meeting of stockholders (if earlier than June 10, 2022). This option was granted based on Mr. Aldrich's election to receive his annual cash compensation in the form of a stock option. /s/ Jeffrey A. Munsie, attorney-in-fact 2021-06-11