X0306 4 2019-04-10 0 0001367920 CONCERT PHARMACEUTICALS, INC. CNCE 0001594857 Tung Roger D C/O CONCERT PHARMACEUTICALS, INC. 65 HAYDEN AVENUE, SUITE 3000N LEXINGTON MA 02421 1 1 0 0 Chief Executive Officer Common Stock 2019-04-10 4 M 0 24886 4.41 A 616919 D Common Stock 121873 I By Roger D. Tung 2011 GRAT Common Stock 13274 I By Tung Family Investment Trust Common Stock 12389 I By RD Tung Irrevocable Trust Employee Stock Option (right to buy) 4.41 2019-04-10 4 M 0 24886 0.00 D 2019-12-10 Common Stock 24886 13166 D Shares held by Roger D. Tung 2011 GRAT. Dr. Tung is the sole trustee of the Roger D. Tung 2011 GRAT. Dr. Tung disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. Shares held by the Tung Family Investment Trust. Dr. Tung is a co-trustee of the Tung Family Investment Trust. Dr. Tung disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. Shares held by the RD Tung Irrevocable Trust. Dr. Tung's spouse is a co-trustee of the RD Tung Irrevocable Trust. Dr. Tung disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. Immediately. /s/ Roger D. Tung 2019-04-10