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Income taxes - Narrative (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Income Tax Contingency [Line Items]        
Valuation allowance increase, including CTA component $ 37.8      
Deferred tax liabilities, foreign withholding tax 4.7 $ 0.0    
Valuation allowance increase $ 37.8      
Effective income tax rate reconciliation, percent 3.00% 28.00% 26.00%  
Unrecognized tax benefits, noncurrent $ 6.8 $ 12.7    
Gross unrecognized tax benefits 6.8 12.7 $ 12.2 $ 8.9
Unrecognized tax benefits, reduction resulting from lapse of applicable statute of limitations 5.1 0.0 0.0  
Unrecognized tax benefits, income tax penalties and interest accrued 1.6 3.7    
Unrecognized tax benefits, income tax penalties and interest expense (2.1) $ 1.1 $ 0.4  
Domestic Tax Authority        
Income Tax Contingency [Line Items]        
Operating loss carryforwards 70.5      
Operating loss carryforwards, subject to expiration 36.0      
Operating loss carryforwards, not subject to expiration 34.5      
Tax credit carryforward, amount 13.4      
State and Local Jurisdiction | Maryland        
Income Tax Contingency [Line Items]        
Operating loss carryforwards 1,700.0      
State and Local Jurisdiction | California        
Income Tax Contingency [Line Items]        
Operating loss carryforwards 146.5      
State and Local Jurisdiction | Research Tax Credit Carryforward        
Income Tax Contingency [Line Items]        
Tax credit carryforward, amount 5.0      
Foreign Tax Authority        
Income Tax Contingency [Line Items]        
Operating loss carryforwards 51.5      
Operating loss carryforwards, subject to expiration 14.5      
Operating loss carryforwards, not subject to expiration 37.0      
PaxVax        
Income Tax Contingency [Line Items]        
Unrecognized tax benefits, reduction resulting from lapse of applicable statute of limitations $ 8.0