Revenue recognition - Disaggregation of Revenue (Details) - USD ($) $ in Millions	3 Months Ended								12 Months Ended
	Dec. 31, 2022	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Dec. 31, 2021	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Disaggregation of Revenue [Line Items]
Leases									$ 4.9
Total revenues	$ 330.2	$ 239.9	$ 242.6	$ 304.8	$ 732.9	$ 286.3	$ 377.4	$ 377.0	1,117.5	$ 1,773.6	$ 1,577.3
USG
Disaggregation of Revenue [Line Items]
Total revenues									482.6	903.3	983.0
Non-USG
Disaggregation of Revenue [Line Items]
Total revenues									634.9	870.3	594.3
Product sales, net
Disaggregation of Revenue [Line Items]
Revenue									966.2	1,023.9	989.8
Product sales, net | USG
Disaggregation of Revenue [Line Items]
Revenue									445.4	530.0	626.0
Product sales, net | Non-USG
Disaggregation of Revenue [Line Items]
Revenue									520.8	493.9	363.8
Total CDMO
Disaggregation of Revenue [Line Items]
Total CDMO									109.9	615.5	472.4
Total CDMO | USG
Disaggregation of Revenue [Line Items]
Total CDMO									0.0	243.1	247.8
Total CDMO | Non-USG
Disaggregation of Revenue [Line Items]
Total CDMO									109.9	372.4	224.6
Services
Disaggregation of Revenue [Line Items]
Revenue									105.0	310.3	194.1
Services | USG
Disaggregation of Revenue [Line Items]
Revenue									0.0	0.0	0.0
Services | Non-USG
Disaggregation of Revenue [Line Items]
Revenue									105.0	310.3	194.1
Leases
Disaggregation of Revenue [Line Items]
Leases									4.9	305.2	278.3
Leases | USG
Disaggregation of Revenue [Line Items]
Leases									0.0	243.1	247.8
Leases | Non-USG
Disaggregation of Revenue [Line Items]
Leases									4.9	62.1	30.5
Contracts and grants
Disaggregation of Revenue [Line Items]
Revenue									41.4	134.2	115.1
Contracts and grants | USG
Disaggregation of Revenue [Line Items]
Revenue									37.2	130.2	109.2
Contracts and grants | Non-USG
Disaggregation of Revenue [Line Items]
Revenue									$ 4.2	$ 4.0	$ 5.9