Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions	3 Months Ended								12 Months Ended
	Dec. 31, 2022	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Dec. 31, 2021	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenues:
Leases									$ 4.9
Total revenues	$ 330.2	$ 239.9	$ 242.6	$ 304.8	$ 732.9	$ 286.3	$ 377.4	$ 377.0	1,117.5	$ 1,773.6	$ 1,577.3
Operating expenses:
Cost of goods and services sold									693.1	748.1	537.0
Research and development									188.3	235.2	237.9
Selling, general and administrative									339.5	348.7	304.1
Goodwill impairment									6.7	41.7	0.0
Amortization of intangible assets									59.9	58.5	59.8
Total operating expenses									1,287.5	1,432.2	1,138.8
Income (loss) from operations	(55.3)	(45.3)	(76.3)	6.9	286.8	(44.7)	7.1	92.2	(170.0)	341.4	438.5
Other income (expense):
Interest expense									(37.3)	(34.5)	(31.3)
Other, net									(11.7)	(3.7)	4.7
Total other income (expense), net									(49.0)	(38.2)	(26.6)
Income (loss) before income taxes									(219.0)	303.2	411.9
Income tax (benefit) provision									(7.4)	83.7	106.1
Net income (loss)	$ (67.0)	$ (87.1)	$ (52.9)	$ (4.6)	$ 193.1	$ (40.4)	$ (0.5)	$ 67.3	$ (211.6)	$ 219.5	$ 305.8
Net income (loss) per common share
Basic (in dollars per share)	$ (1.34)	$ (1.75)	$ (1.06)	$ (0.09)	$ 3.62	$ (0.75)	$ (0.01)	$ 1.26	$ (4.22)	$ 4.10	$ 5.80
Diluted (in dollars per share)	$ (1.34)	$ (1.75)	$ (1.06)	$ (0.09)	$ 3.60	$ (0.75)	$ (0.01)	$ 1.23	$ (4.22)	$ 4.06	$ 5.68
Shares used in computing net income (loss) per common share
Basic (in shares)									50.1	53.5	52.7
Diluted (in shares)									50.1	54.1	53.8
Product sales, net
Revenues:
Services									$ 966.2	$ 1,023.9	$ 989.8
Operating expenses:
Cost of goods and services sold	$ 167.8	$ 85.2	$ 92.2	$ 79.4	$ 144.1	$ 104.3	$ 81.4	$ 52.8	424.6	382.6	392.0
Total CDMO
Revenues:
Total CDMO									109.9	615.5	472.4
Operating expenses:
Cost of goods and services sold	$ 52.7	$ 62.0	$ 79.8	$ 74.0	$ 69.7	$ 77.5	$ 133.9	$ 84.4	268.5	365.5	145.0
Services
Revenues:
Services									105.0	310.3	194.1
Leases
Revenues:
Leases									4.9	305.2	278.3
Contracts and grants
Revenues:
Services									$ 41.4	$ 134.2	$ 115.1