Revenue recognition - Disaggregation of Revenue (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Disaggregation of Revenue [Line Items]
Leases	$ 4.9
Total revenues	1,120.9	$ 1,792.7	$ 1,555.4
USG
Disaggregation of Revenue [Line Items]
Total revenues	482.6	897.8	988.5
Non-USG
Disaggregation of Revenue [Line Items]
Total revenues	638.3	894.9	566.9
Product sales, net
Disaggregation of Revenue [Line Items]
Revenue	966.2	1,023.9	989.8
Product sales, net | USG
Disaggregation of Revenue [Line Items]
Revenue	445.4	530.0	626.0
Product sales, net | Non-USG
Disaggregation of Revenue [Line Items]
Revenue	520.8	493.9	363.8
Total CDMO
Disaggregation of Revenue [Line Items]
Total CDMO	113.3	634.6	450.5
Total CDMO | USG
Disaggregation of Revenue [Line Items]
Total CDMO	0.0	237.6	253.3
Total CDMO | Non-USG
Disaggregation of Revenue [Line Items]
Total CDMO	113.3	397.0	197.2
Services
Disaggregation of Revenue [Line Items]
Revenue	108.4	334.9	166.7
Services | USG
Disaggregation of Revenue [Line Items]
Revenue	0.0	0.0	0.0
Services | Non-USG
Disaggregation of Revenue [Line Items]
Revenue	108.4	334.9	166.7
Leases
Disaggregation of Revenue [Line Items]
Leases	4.9	299.7	283.8
Leases | USG
Disaggregation of Revenue [Line Items]
Leases	0.0	237.6	253.3
Leases | Non-USG
Disaggregation of Revenue [Line Items]
Leases	4.9	62.1	30.5
Contracts and grants
Disaggregation of Revenue [Line Items]
Revenue	41.4	134.2	115.1
Contracts and grants | USG
Disaggregation of Revenue [Line Items]
Revenue	37.2	130.2	109.2
Contracts and grants | Non-USG
Disaggregation of Revenue [Line Items]
Revenue	$ 4.2	$ 4.0	$ 5.9