Condensed Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenues:
Total revenues	$ 240.0	$ 329.0	$ 790.2	$ 1,069.5
Operating expenses:
Research and development	39.2	49.6	135.4	151.0
Selling, general and administrative	80.2	82.1	246.1	254.2
Amortization of intangible assets	14.0	14.5	42.0	44.5
Total operating expenses	282.0	363.7	897.8	994.3
Income (loss) from operations	(42.0)	(34.7)	(107.6)	75.2
Other income (expense):
Interest expense	(8.5)	(8.4)	(24.5)	(25.5)
Other, net	(13.4)	(2.4)	(18.4)	(2.8)
Total other income (expense), net	(21.9)	(10.8)	(42.9)	(28.3)
Income (loss) before income taxes	(63.9)	(45.5)	(150.5)	46.9
Income tax benefit (provision)	(11.8)	12.8	14.7	(5.3)
Net income (loss)	$ (75.7)	$ (32.7)	$ (135.8)	$ 41.6
Net income (loss) per common share
Basic (in dollars per share)	$ (1.52)	$ (0.61)	$ (2.71)	$ 0.78
Diluted (in dollars per share)	$ (1.52)	$ (0.61)	$ (2.71)	$ 0.77
Shares used in computing net loss per common share
Basic (in shares)	49.9	53.7	50.2	53.6
Diluted (in shares)	49.9	53.7	50.2	54.3
Product sales, net
Revenues:
Services	$ 186.2	$ 270.5	$ 660.5	$ 589.6
Operating expenses:
Cost of goods and services sold	85.5	103.2	256.8	237.0
Total CDMO
Revenues:
Total CDMO	36.4	41.6	95.4	416.3
Services
Revenues:
Services	36.2	112.6	90.7	283.7
Operating expenses:
Cost of goods and services sold	63.1	114.3	217.5	307.6
Leases
Revenues:
Leases	0.2	(71.0)	4.7	132.6
Contracts and grants
Revenues:
Services	$ 17.4	$ 16.9	$ 34.3	$ 63.6