Equity (Tables)

9 Months Ended

Sep. 30, 2022

Stockholders' Equity Note [Abstract]

Share-based Payment Arrangement, Expensed and Capitalized, Amount

Share-based compensation expense was recorded in the following financial statement line items:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2022		2021		2022		2021
Cost of product sales	$	1.8	$	1.3	$	5.4	$	4.5
Cost of CDMO	0.4		0.3		1.4		0.8
Research and development	1.3		1.4		3.9		4.5
Selling, general and administrative	7.7		7.4		22.7		22.5
Total share-based compensation expense	$	11.2	$	10.4	$	33.4	$	32.3

Schedule of Accumulated Other Comprehensive Income (Loss)

The following table includes changes in accumulated other comprehensive loss, net of tax by component:

	Defined Benefit Pension Plan		Derivative Instruments		Foreign Currency Translation Adjustments		Total
Balance, December 31, 2021	$	(4.0)	$	(4.5)	$	(7.6)	$	(16.1)
Other comprehensive income (loss) before reclassifications	—		9.4		(0.4)		9.0
Amounts reclassified from accumulated other comprehensive loss	—		1.9		—		1.9
Net current period other comprehensive income (loss)	—		11.3		(0.4)		10.9
Balance, September 30, 2022	$	(4.0)	$	6.8	$	(8.0)	$	(5.2)
Balance, June 30, 2022	$	(4.0)	$	4.6	$	(6.7)	$	(6.1)
Other comprehensive income (loss) before reclassifications	—		2.6		(1.3)		1.3
Amounts reclassified from accumulated other comprehensive loss	—		(0.4)		—		(0.4)
Net current period other comprehensive income (loss)	—		2.2		(1.3)		0.9
Balance, September 30, 2022	$	(4.0)	$	6.8	$	(8.0)	$	(5.2)
Balance, December 31, 2020	$	(7.7)	$	(11.0)	$	(6.6)	$	(25.3)
Other comprehensive loss before reclassifications	—		(0.7)		(1.4)		(2.1)
Amounts reclassified from accumulated other comprehensive loss	—		4.3		—		4.3
Net current period other comprehensive income (loss)	—		3.6		(1.4)		2.2
Balance, September 30, 2021	$	(7.7)	$	(7.4)	$	(8.0)	$	(23.1)
Balance, June 30, 2021	$	(7.7)	$	(6.4)	$	(8.3)	$	(22.4)
Other comprehensive income (loss) before reclassifications	—		(2.3)		0.3		(2.0)
Amounts reclassified from accumulated other comprehensive loss	—		1.3		—		1.3
Net current period other comprehensive income (loss)	—		(1.0)		0.3		(0.7)
Balance, September 30, 2021	$	(7.7)	$	(7.4)	$	(8.0)	$	(23.1)

Comprehensive Income (Loss)

The tables below present the tax effects related to each component of other comprehensive income (loss):

	Three Months Ended September 30,
	2022						2021
	Pretax		Tax Expense		Net of tax		Pretax		Tax Expense		Net of tax
Derivative instruments	$	3.0	$	(0.8)	$	2.2	$	1.3	$	(2.3)	$	(1.0)
Foreign currency translation adjustments	0.1		(1.4)		(1.3)		0.3		—		0.3
Total adjustments	$	3.1	$	(2.2)	$	0.9	$	1.6	$	(2.3)	$	(0.7)

	Nine Months Ended September 30,
	2022						2021
	Pretax		Tax Expense		Net of tax		Pretax		Tax Expense		Net of tax
Derivative instruments	$	15.4	$	(4.1)	$	11.3	$	4.9	$	(1.3)	$	3.6
Foreign currency translation adjustments	2.1		(2.5)		(0.4)		(1.4)		—		(1.4)
Total adjustments	$	17.5	$	(6.6)	$	10.9	$	3.5	$	(1.3)	$	2.2